Literature DB >> 30518611

Wireless, battery-free, flexible, miniaturized dosimeters monitor exposure to solar radiation and to light for phototherapy.

Seung Yun Heo1, Jeonghyun Kim2, Philipp Gutruf3, Anthony Banks4,5,6, Pinghung Wei7,8, Rafal Pielak7,8, Guive Balooch7,8, Yunzhou Shi7,8, Hitoshi Araki9, Derrick Rollo10, Carey Gaede10, Manish Patel4, Jean Won Kwak11, Amnahir E Peña-Alcántara12, Kyu-Tae Lee13, Yeojeong Yun5, June K Robinson14, Shuai Xu15,16, John A Rogers17.   

Abstract

Exposure to electromagnetic radiation can have a profound impact on human health. Ultraviolet (UV) radiation from the sun causes skin cancer. Blue light affects the body's circadian melatonin rhythm. At the same time, electromagnetic radiation in controlled quantities has beneficial use. UV light treats various inflammatory skin conditions, and blue light phototherapy is the standard of care for neonatal jaundice. Although quantitative measurements of exposure in these contexts are important, current systems have limited applicability outside of laboratories because of an unfavorable set of factors in bulk, weight, cost, and accuracy. We present optical metrology approaches, optoelectronic designs, and wireless modes of operation that serve as the basis for miniature, low-cost, and battery-free devices for precise dosimetry at multiple wavelengths. These platforms use a system on a chip with near-field communication functionality, a radio frequency antenna, photodiodes, supercapacitors, and a transistor to exploit a continuous accumulation mechanism for measurement. Experimental and computational studies of the individual components, the collective systems, and the performance parameters highlight the operating principles and design considerations. Evaluations on human participants monitored solar UV exposure during outdoor activities, captured instantaneous and cumulative exposure during blue light phototherapy in neonatal intensive care units, and tracked light illumination for seasonal affective disorder phototherapy. Versatile applications of this dosimetry platform provide means for consumers and medical providers to modulate light exposure across the electromagnetic spectrum in a way that can both reduce risks in the context of excessive exposure and optimize benefits in the context of phototherapy.
Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

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Year:  2018        PMID: 30518611      PMCID: PMC6361379          DOI: 10.1126/scitranslmed.aau1643

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN: 1946-6234            Impact factor:   17.956


  27 in total

1.  The measurement of solar ultraviolet radiation.

Authors:  C R Roy; H P Gies; D J Lugg; S Toomey; D W Tomlinson
Journal:  Mutat Res       Date:  1998-11-09       Impact factor: 2.433

2.  Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States.

Authors:  Lola Rahib; Benjamin D Smith; Rhonda Aizenberg; Allison B Rosenzweig; Julie M Fleshman; Lynn M Matrisian
Journal:  Cancer Res       Date:  2014-06-01       Impact factor: 12.701

3.  Phototherapy of jaundice in the newborn infant. II. Effect of various light intensities.

Authors:  T R Sisson; N Kendall; E Shaw; L Kechavarz-Oliai
Journal:  J Pediatr       Date:  1972-07       Impact factor: 4.406

4.  Flexible Near-Field Wireless Optoelectronics as Subdermal Implants for Broad Applications in Optogenetics.

Authors:  Gunchul Shin; Adrian M Gomez; Ream Al-Hasani; Yu Ra Jeong; Jeonghyun Kim; Zhaoqian Xie; Anthony Banks; Seung Min Lee; Sang Youn Han; Chul Jong Yoo; Jong-Lam Lee; Seung Hee Lee; Jonas Kurniawan; Jacob Tureb; Zhongzhu Guo; Jangyeol Yoon; Sung-Il Park; Sang Yun Bang; Yoonho Nam; Marie C Walicki; Vijay K Samineni; Aaron D Mickle; Kunhyuk Lee; Seung Yun Heo; Jordan G McCall; Taisong Pan; Liang Wang; Xue Feng; Tae-Il Kim; Jong Kyu Kim; Yuhang Li; Yonggang Huang; Robert W Gereau; Jeong Sook Ha; Michael R Bruchas; John A Rogers
Journal:  Neuron       Date:  2017-01-26       Impact factor: 17.173

5.  The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidence.

Authors:  Robert N Golden; Bradley N Gaynes; R David Ekstrom; Robert M Hamer; Frederick M Jacobsen; Trisha Suppes; Katherine L Wisner; Charles B Nemeroff
Journal:  Am J Psychiatry       Date:  2005-04       Impact factor: 18.112

6.  The other end of the rainbow: infrared and skin.

Authors:  Aton M Holzer; Mohammad Athar; Craig A Elmets
Journal:  J Invest Dermatol       Date:  2010-06       Impact factor: 8.551

7.  No end in sight: the skin cancer epidemic continues.

Authors:  Matthew R Donaldson; Brett M Coldiron
Journal:  Semin Cutan Med Surg       Date:  2011-03

8.  Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation.

Authors: 
Journal:  Pediatrics       Date:  2004-07       Impact factor: 7.124

9.  Battery-free, stretchable optoelectronic systems for wireless optical characterization of the skin.

Authors:  Jeonghyun Kim; Giovanni A Salvatore; Hitoshi Araki; Antonio M Chiarelli; Zhaoqian Xie; Anthony Banks; Xing Sheng; Yuhao Liu; Jung Woo Lee; Kyung-In Jang; Seung Yun Heo; Kyoungyeon Cho; Hongying Luo; Benjamin Zimmerman; Joonhee Kim; Lingqing Yan; Xue Feng; Sheng Xu; Monica Fabiani; Gabriele Gratton; Yonggang Huang; Ungyu Paik; John A Rogers
Journal:  Sci Adv       Date:  2016-08-03       Impact factor: 14.136

10.  Beyond Abandonment to Next Steps: Understanding and Designing for Life after Personal Informatics Tool Use.

Authors:  Daniel A Epstein; Monica Caraway; Chuck Johnston; An Ping; James Fogarty; Sean A Munson
Journal:  Proc SIGCHI Conf Hum Factor Comput Syst       Date:  2016-05
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  11 in total

Review 1.  Wireless and battery-free platforms for collection of biosignals.

Authors:  Tucker Stuart; Le Cai; Alex Burton; Philipp Gutruf
Journal:  Biosens Bioelectron       Date:  2021-01-23       Impact factor: 10.618

2.  Sun exposure reduction by melanoma survivors with wearable sensor providing real-time UV exposure and daily text messages with structured goal setting.

Authors:  June K Robinson; Dalya A Durst; Elizabeth Gray; Mary Kwasny; Seung Yun Heo; Anthony Banks; John A Rogers
Journal:  Arch Dermatol Res       Date:  2020-11-13       Impact factor: 3.033

3.  Miniaturized, light-adaptive, wireless dosimeters autonomously monitor exposure to electromagnetic radiation.

Authors:  Kyeongha Kwon; Seung Yun Heo; Injae Yoo; Anthony Banks; Michelle Chan; Jong Yoon Lee; Jun Bin Park; Jeonghyun Kim; John A Rogers
Journal:  Sci Adv       Date:  2019-12-13       Impact factor: 14.136

4.  Wireless, implantable catheter-type oximeter designed for cardiac oxygen saturation.

Authors:  Wei Lu; Wubin Bai; Hao Zhang; Chenkai Xu; Antonio M Chiarelli; Abraham Vázquez-Guardado; Zhaoqian Xie; Haixu Shen; Khizar Nandoliya; Hangbo Zhao; KunHyuck Lee; Yixin Wu; Daniel Franklin; Raudel Avila; Shuai Xu; Alina Rwei; Mengdi Han; Kyeongha Kwon; Yujun Deng; Xinge Yu; Edward B Thorp; Xue Feng; Yonggang Huang; Joseph Forbess; Zhi-Dong Ge; John A Rogers
Journal:  Sci Adv       Date:  2021-02-10       Impact factor: 14.136

Review 5.  Near-Field Communication in Biomedical Applications.

Authors:  Sung-Gu Kang; Min-Su Song; Joon-Woo Kim; Jung Woo Lee; Jeonghyun Kim
Journal:  Sensors (Basel)       Date:  2021-01-20       Impact factor: 3.576

6.  Real-Time UV Measurement With a Sun Protection System for Warning Young Adults About Sunburn: Prospective Cohort Study.

Authors:  June K Robinson; Shiv Patel; Seung Yun Heo; Elizabeth Gray; Jaeman Lim; Kyeongha Kwon; Zach Christiansen; Jeffrey Model; Jacob Trueb; Anthony Banks; Mary Kwasny; John A Rogers
Journal:  JMIR Mhealth Uhealth       Date:  2021-05-06       Impact factor: 4.773

7.  Fabrication of a Flexible, Wireless Micro-Heater on Elastomer for Wearable Gas Sensor Applications.

Authors:  Jonam Cho; Gunchul Shin
Journal:  Polymers (Basel)       Date:  2022-04-11       Impact factor: 4.967

8.  Digitally-embroidered liquid metal electronic textiles for wearable wireless systems.

Authors:  Rongzhou Lin; Han-Joon Kim; Sippanat Achavananthadith; Ze Xiong; Jason K W Lee; Yong Lin Kong; John S Ho
Journal:  Nat Commun       Date:  2022-04-21       Impact factor: 17.694

9.  Transcriptomic profile of adverse neurodevelopmental outcomes after neonatal encephalopathy.

Authors:  Myrsini Kaforou; Jethro Herberg; Sudhin Thayyil; Paolo Montaldo; Aubrey Cunnington; Vania Oliveira; Ravi Swamy; Prathik Bandya; Stuti Pant; Peter J Lally; Phoebe Ivain; Josephine Mendoza; Gaurav Atreja; Vadakepat Padmesh; Mythili Baburaj; Monica Sebastian; Indiramma Yasashwi; Chinnathambi Kamalarathnam; Rema Chandramohan; Sundaram Mangalabharathi; Kumutha Kumaraswami; Shobha Kumar; Naveen Benakappa; Swati Manerkar; Jayashree Mondhkar; Vinayagam Prakash; Mohammed Sajjid; Arasar Seeralar; Ismat Jahan; Sadeka Choudhury Moni; Mohammod Shahidullah; Radhika Sujatha; Manigandan Chandrasekaran; Siddarth Ramji; Seetha Shankaran
Journal:  Sci Rep       Date:  2020-08-04       Impact factor: 4.379

10.  Wireless battery-free body sensor networks using near-field-enabled clothing.

Authors:  Rongzhou Lin; Han-Joon Kim; Sippanat Achavananthadith; Selman A Kurt; Shawn C C Tan; Haicheng Yao; Benjamin C K Tee; Jason K W Lee; John S Ho
Journal:  Nat Commun       Date:  2020-01-23       Impact factor: 14.919

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