Literature DB >> 30517970

Impact of Electronic Physician Order-Set on Antibiotic Ordering Time in Septic Patients in the Emergency Department.

Emily L Fargo1, Frank D'Amico1, Aaron Pickering1, Kathleen Fowler2, Ronald Campbell1, Megan Baumgartner1.   

Abstract

BACKGROUND: Sepsis is a serious medical condition that can lead to organ dysfunction and death. Research shows that each hour delay in antibiotic administration increases mortality. The Surviving Sepsis Campaign Bundles created standards to assist in the timely treatment of patients with suspected sepsis to improve outcomes and reduce mortality.
OBJECTIVE: This article determines if the use of an electronic physician order-set decreases time to antibiotic ordering for patients with sepsis in the emergency department (ED).
METHODS: A retrospective chart review was performed on adult patients who presented to the ED of four community hospitals from May to July 2016. Patients with severe sepsis and/or septic shock were included. Primary outcome was the difference in time to antibiotic ordering in patients whose physicians utilized the order-set versus those whose physicians did not. Secondary outcomes included differences in time to antibiotic administration, time to lactate test, hospital length of stay, and posthospitalization disposition. The institution's Quality Improvement Committee approved the project.
RESULTS: Forty-five of 123 patients (36.6%) with sepsis had physicians who used the order-set. Order-set utilization reduced the mean time to ordering antibiotics by 20 minutes (99 minutes, 95% confidence interval [CI]: 69-128 vs. 119 minutes, 95% CI: 91-147), but this finding was not statistically significant. Mean time to antibiotic administration (145 minutes, 95% CI: 108-181 vs. 182 minutes, 95% CI: 125-239) and median time to lactate tests (12 minutes, 95% CI: 0-20 vs. 19 minutes, 95% CI: 8-34), although in the direction of the hypotheses, were not significantly different.
CONCLUSION: Utilization of the order-set was associated with a potentially clinically significant, but not statistically significant, reduced time to antibiotic ordering in patients with sepsis. Electronic order-sets are a promising tool to assist hospitals with meeting the Centers for Medicare and Medicaid Services core measure. Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2018        PMID: 30517970      PMCID: PMC6281440          DOI: 10.1055/s-0038-1676040

Source DB:  PubMed          Journal:  Appl Clin Inform        ISSN: 1869-0327            Impact factor:   2.342


  18 in total

1.  Early goal-directed therapy in the treatment of severe sepsis and septic shock.

Authors:  E Rivers; B Nguyen; S Havstad; J Ressler; A Muzzin; B Knoblich; E Peterson; M Tomlanovich
Journal:  N Engl J Med       Date:  2001-11-08       Impact factor: 91.245

2.  Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.

Authors:  Anand Kumar; Daniel Roberts; Kenneth E Wood; Bruce Light; Joseph E Parrillo; Satendra Sharma; Robert Suppes; Daniel Feinstein; Sergio Zanotti; Leo Taiberg; David Gurka; Aseem Kumar; Mary Cheang
Journal:  Crit Care Med       Date:  2006-06       Impact factor: 7.598

3.  Prospective trial of real-time electronic surveillance to expedite early care of severe sepsis.

Authors:  Jessica L Nelson; Barbara L Smith; Jeremy D Jared; John G Younger
Journal:  Ann Emerg Med       Date:  2011-01-12       Impact factor: 5.721

4.  The Surviving Sepsis Campaign Bundle: 2018 Update.

Authors:  Mitchell M Levy; Laura E Evans; Andrew Rhodes
Journal:  Crit Care Med       Date:  2018-06       Impact factor: 7.598

5.  Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: results from a guideline-based performance improvement program.

Authors:  Ricard Ferrer; Ignacio Martin-Loeches; Gary Phillips; Tiffany M Osborn; Sean Townsend; R Phillip Dellinger; Antonio Artigas; Christa Schorr; Mitchell M Levy
Journal:  Crit Care Med       Date:  2014-08       Impact factor: 7.598

6.  Developing an early sepsis alert program.

Authors:  Kristen M Buck
Journal:  J Nurs Care Qual       Date:  2014 Apr-Jun       Impact factor: 1.597

7.  Sepsis Early Alert Tool: Early recognition and timely management in the emergency department.

Authors:  Marwan Idrees; Stephen Pj Macdonald; Kiren Kodali
Journal:  Emerg Med Australas       Date:  2016-05-05       Impact factor: 2.151

8.  A targeted real-time early warning score (TREWScore) for septic shock.

Authors:  Katharine E Henry; David N Hager; Peter J Pronovost; Suchi Saria
Journal:  Sci Transl Med       Date:  2015-08-05       Impact factor: 17.956

9.  The impact of compliance with 6-hour and 24-hour sepsis bundles on hospital mortality in patients with severe sepsis: a prospective observational study.

Authors:  Fang Gao; Teresa Melody; Darren F Daniels; Simon Giles; Samantha Fox
Journal:  Crit Care       Date:  2005-11-11       Impact factor: 9.097

10.  Automated electronic medical record sepsis detection in the emergency department.

Authors:  Su Q Nguyen; Edwin Mwakalindile; James S Booth; Vicki Hogan; Jordan Morgan; Charles T Prickett; John P Donnelly; Henry E Wang
Journal:  PeerJ       Date:  2014-04-10       Impact factor: 2.984

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  5 in total

1.  Comparison of Antibiotic Dosing Before and After Implementation of an Electronic Order Set.

Authors:  Kristen R Nichols; Allison L Petschke; Emily C Webber; Chad A Knoderer
Journal:  Appl Clin Inform       Date:  2019-04-03       Impact factor: 2.342

2.  The Impact of Changes to an Electronic Admission Order Set on Prescribing and Clinical Outcomes in the Intensive Care Unit.

Authors:  Ellen T Muniga; Todd A Walroth; Natalie C Washburn
Journal:  Appl Clin Inform       Date:  2020-03-11       Impact factor: 2.342

3.  Sustained Improvement in Inflammatory Bowel Disease Quality Measures Using an Electronic Health Record Intervention.

Authors:  Andrew Bensinger; Farra Wilson; Patrick Green; Richard Bloomfeld; Ajay Dharod
Journal:  Appl Clin Inform       Date:  2019-12-04       Impact factor: 2.342

4.  Quality initiative to improve emergency department sepsis bundle compliance through utilisation of an electronic health record tool.

Authors:  Nicholus Michael Warstadt; J Reed Caldwell; Nicole Tang; Staci Mandola; Catherine Jamin; Cassidy Dahn
Journal:  BMJ Open Qual       Date:  2022-01

Review 5.  Antimicrobial stewardship using electronic prescribing systems in hospital settings: a scoping review of interventions and outcome measures.

Authors:  J A Jenkins; S K Pontefract; K Cresswell; R Williams; A Sheikh; J J Coleman
Journal:  JAC Antimicrob Resist       Date:  2022-06-28
  5 in total

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