Literature DB >> 30517348

The impact of pneumococcal vaccine in reducing pneumonia hospitalizations in children under 5 years old, in Santa Catarina, Brazil, 2006 a 2014.

Ilse Lisiane Viertel Vieira1, Emil Kupek1.   

Abstract

OBJECTIVE: to analyze the impact of pneumococcal conjugate vaccine (PCV10) on pneumonia hospital admissions among children in Santa Catarina, Brazil, 2006-2014.
METHODS: this was an ecological study using data obtained from Brazilian National Health System Information Technology Department (Datasus) for 2006-2009 (pre-vaccination period) and 2010-2014 (post-vaccination period); time trends were evaluated using the Poisson regression coefficient.
RESULTS: in the comparison between pre- and post-vaccination periods, the percentage difference in the hospitalization rate for children under 1 year old ranged from -44.1% in the Western region to -1.4% in the Serrano Plateau region, and in children between 1-4 years old it ranged from -37.1% in the Northern Plateau region to 16.9% in the Serrano Plateau region (p<0.05); hospitalization rates in the state reduced by 23.3% in children under 1 year old and by 8.4% in those aged 1-4 years.
CONCLUSION: a significant reduction in the rate of pneumonia hospitalization in children under 1 year old age was found, suggesting the effectiveness of the vaccine in reducing hospitalizations.

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Year:  2018        PMID: 30517348     DOI: 10.5123/S1679-49742018000400012

Source DB:  PubMed          Journal:  Epidemiol Serv Saude        ISSN: 1679-4974


  1 in total

1.  Impact after 10-year use of pneumococcal conjugate vaccine in the Brazilian national immunization program: an updated systematic literature review from 2015 to 2020.

Authors:  Adriana Guzman-Holst; Eliana de Barros; Pilar Rubio; Rodrigo DeAntonio; Otavio Cintra; Ariane Abreu
Journal:  Hum Vaccin Immunother       Date:  2021-03-18       Impact factor: 3.452

  1 in total

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