Literature DB >> 30516789

Copper-catalyzed three-component synthesis of pyrimidines from amidines and alcohols.

Tianchao Shi1, Feng Qin, Qian Li, Wu Zhang.   

Abstract

An efficient copper-catalyzed one-pot three-component reaction of amidines, primary alcohols and secondary alcohols has been developed to synthesize multisubstituted pyrimidines. The significant merits of this method involve high atom efficiency, good functional group tolerance and operational simplicity.

Entities:  

Year:  2018        PMID: 30516789     DOI: 10.1039/c8ob02694g

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

Review 1.  Recent developments and perspectives in the copper-catalyzed multicomponent synthesis of heterocycles.

Authors:  Jaleel Fairoosa; Mohan Neetha; Gopinathan Anilkumar
Journal:  RSC Adv       Date:  2021-01-15       Impact factor: 3.361

  1 in total

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