Literature DB >> 30516782

Ring-closing metathesis of unprotected peptides in water.

Shun Masuda1, Shugo Tsuda, Taku Yoshiya.   

Abstract

Ring-closing metathesis (RCM) is an attractive reaction for the preparation of artificially designed peptides. Until now, RCM has been used for fully or partially protected peptides. Herein, the first RCM of unprotected peptides in water was achieved using a water-soluble Ru catalyst.

Entities:  

Year:  2018        PMID: 30516782     DOI: 10.1039/c8ob02778a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  2 in total

1.  Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries.

Authors:  Olivier B C Monty; Pranavanand Nyshadham; Kurt M Bohren; Murugesan Palaniappan; Martin M Matzuk; Damian W Young; Nicholas Simmons
Journal:  ACS Comb Sci       Date:  2020-01-21       Impact factor: 3.784

2.  It is Better with Salt: Aqueous Ring-Opening Metathesis Polymerization at Neutral pH.

Authors:  Jeffrey C Foster; Marcus C Grocott; Lucy A Arkinstall; Spyridon Varlas; McKenna J Redding; Scott M Grayson; Rachel K O'Reilly
Journal:  J Am Chem Soc       Date:  2020-08-03       Impact factor: 15.419

  2 in total

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