Literature DB >> 30516718

Comparison of the Effects of Epidural Analgesia and Patient-controlled Intravenous Analgesia on Postoperative Pain Relief and Recovery After Laparoscopic Gastrectomy for Gastric Cancer.

Satoru Kikuchi1, Shinji Kuroda1, Masahiko Nishizaki1, Takashi Matsusaki2, Kazuya Kuwada1, Yoshikazu Kimura2, Shunsuke Kagawa1, Hiroshi Morimatsu2, Toshiyoshi Fujiwara1.   

Abstract

PURPOSE: Epidural analgesia (EDA) is an imperative modality for postoperative pain relief after major open abdominal surgery. However, whether EDA has benefits in laparoscopic surgery has not been clear. In this study, the effects of EDA and patient-controlled intravenous analgesia (PCIA) after laparoscopic distal gastrectomy (LDG) were compared.
METHODS: This was a retrospective study that included 82 patients undergoing LDG for gastric cancer. Patients received either EDA (n=67) or PCIA (n=15) for postoperative pain relief. Postoperative outcomes and analgesia-related adverse events were compared between the two modalities.
RESULTS: EDA and PCIA patients showed no differences in the incidence of complications [9 (13%) vs. 2 (13%); P=0.99] and the length of postoperative hospital stay (9.6±4.5 d vs. 9.7±4.0 d; P=0.90), although the PCIA included poorer preoperative physical status (PS) patients. The number of additional doses of analgesics was higher in the EDA than in the PCIA (1.8±2.4 vs. 0.9±1.0; P=0.01), although postoperative pain scores were similar in the 2 groups. Though the time to first passage of flatus was shorter in the EDA (P<0.05), more EDA patients developed postoperative hypotension as an adverse event (P<0.01). The full mobilization day and the day of oral intake tolerance were not significantly different between the 2 groups after surgery.
CONCLUSIONS: After LDG, EDA may not be indispensable, while PCIA may be the optimal modality for providing safe and effective postoperative analgesia and recovery.

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Mesh:

Year:  2019        PMID: 30516718     DOI: 10.1097/SLE.0000000000000605

Source DB:  PubMed          Journal:  Surg Laparosc Endosc Percutan Tech        ISSN: 1530-4515            Impact factor:   1.719


  4 in total

1.  The Effects of Body Mass Index on the Use of Patient-Controlled Intravenous Analgesia After Open Gastrointestinal Tumor Surgery: A Retrospective Analysis.

Authors:  Ting-Ting Li; Liu-Lin Xiong; Jin Huang; Song Wen; Yan-Jun Chen; Ting-Hua Wang; Fei Liu
Journal:  J Pain Res       Date:  2020-10-22       Impact factor: 3.133

2.  Analgesic efficacy of postoperative bilateral, ultrasound-guided, posterior transversus abdominis plane block for laparoscopic colorectal cancer surgery: a randomized, prospective, controlled study.

Authors:  Yang Zhao; Han-Ying Zhang; Zong-Yi Yuan; Yi Han; Yi-Rong Chen; Qi-Lin Liu; Tao Zhu
Journal:  BMC Anesthesiol       Date:  2021-04-06       Impact factor: 2.217

Review 3.  Effects of Perioperative Epidural Analgesia on Cancer Recurrence and Survival.

Authors:  Donghang Zhang; Jingyao Jiang; Jin Liu; Tao Zhu; Han Huang; Cheng Zhou
Journal:  Front Oncol       Date:  2022-01-05       Impact factor: 6.244

4.  Combined lumbar muscle block and perioperative comprehensive patient-controlled intravenous analgesia with butorphanol in gynecological endoscopic surgery.

Authors:  Rong-Yu Zhu; Si-Qu Xiang; Dou-Ren Chen
Journal:  World J Clin Cases       Date:  2021-12-06       Impact factor: 1.337

  4 in total

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