| Literature DB >> 30513321 |
Quan Zhang1, Lin-Fu Liang2, Ze-Hong Miao3, Bin Wu4, Yue-Wei Guo5.
Abstract
Four new polyhydroxylated steroids lobophysterols A-D (1-4), together with two known related compounds sarcophytosterol (5) and klyflaccisteroid B (6), were isolated from the South China Sea soft coral Lobophytum sp. Their structures were elucidated on the basis of spectroscopic analysis and by comparison with those reported in the literature. In bioassay, compound 4 showed weak cytotoxicities against HT-29, SNU-398, and Capan-1 cells.Entities:
Keywords: Cytotoxicity; Lobophysterols A–D; Lobophytum sp.; Polyhydroxylated steroids; Soft coral
Mesh：
Substances：
Year: 2018 PMID： 30513321 DOI： 10.1016/j.steroids.2018.11.015
Source DB: PubMed Journal: Steroids ISSN： 0039-128X Impact factor: 2.668