Retinoblastoma

Retinoblastoma. Retinoblastoma is the most frequent malignant intraocular tumour of childhood. It is a rare disease occurring in very young children. It is a genetic disease due to the mutation of the RB1gene. Today survival is excellent (98%) in developed countries, however lower survival rates are observed in the developing world where children still die of the disease. Visual prognosis depends on the possibility to realize a conservative treatment as well as the size and location of the tumors. The two main presenting signs of retinoblastoma are leukocoria and strabismus. Every suspicion of leukocoria requires prompt fundus examination.