Literature DB >> 305114

Irreversible inhibition of sodium entry sites in frog skin by a photosensitive amiloride analog.

D J Benos, L J Mandel.   

Abstract

A photosensitive binding reaction is described in which an analog of amiloride is bound to sites that control sodium entry into frog skin. This reaction results in irreversible inhibition of net sodium transport.

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Year:  1978        PMID： 305114     DOI： 10.1126/science.305114

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

1.  Identification of the renal Na+/H+ exchanger with N,N'-dicyclohexylcarbodiimide (DCCD) and amiloride analogues.

Authors:  T Friedrich; J Sablotni; G Burckhardt
Journal:  J Membr Biol       Date:  1986       Impact factor: 1.843

2.  The intracellular localization of amiloride in frog skin.

Authors:  J V Briggman; J S Graves; S S Spicer; E J Cragoe
Journal:  Histochem J       Date:  1983-03

3.  Irreversible inhibition of sodium transport by the toad urinary bladder following photolysis of amiloride analogs.

Authors:  M H Cobb; W N Scott
Journal:  Experientia       Date:  1981-01-15

4.  Amiloride-sensitive Na+-H+ antiporter in Escherichia coli.

Authors:  N Mochizuki-Oda; F Oosawa
Journal:  J Bacteriol       Date:  1985-07       Impact factor: 3.490

5.  Structure-activity relationship of amiloride analogs as blockers of epithelial Na channels: I. Pyrazine-ring modifications.

Authors:  J H Li; E J Cragoe; B Lindemann
Journal:  J Membr Biol       Date:  1985       Impact factor: 1.843

6.  On the mechanism of the amiloride-sodium entry site interaction in anuran skin epithelia.

Authors:  D J Benos; L J Mandel; R S Balaban
Journal:  J Gen Physiol       Date:  1979-03       Impact factor: 4.086

7.  Irreversible inhibition of epithelial sodium channels by ultraviolet irradiation.

Authors:  A W Cuthbert; D D Fanestil; F C Herrera; S J Pryn
Journal:  Br J Pharmacol       Date:  1982-11       Impact factor: 8.739

8.  Synthesis and characterization of methylbromoamiloride, a potential biochemical probe of epithelial Na+ channels.

Authors:  K Lazorick; C Miller; S Sariban-Sohraby; D Benos
Journal:  J Membr Biol       Date:  1985       Impact factor: 1.843

9.  Phenamil: an irreversible inhibitor of sodium channels in the toad urinary bladder.

Authors:  J L Garvin; S A Simon; E J Cragoe; L J Mandel
Journal:  J Membr Biol       Date:  1985       Impact factor: 1.843
  9 in total

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