Literature DB >> 3050986

The B- to Z-DNA equilibrium in vivo is perturbed by biological processes.

W Zacharias1, A Jaworski, J E Larson, R D Wells.   

Abstract

Right-handed B and left-handed Z conformations coexist in equilibrium in portions of plasmids in Escherichia coli. The equilibria are influenced by the length of the sequences that undergo the structural transitions and are perturbed by biological processes. The composite results of three types of determinations indicate a supercoil density of -0.025 in vivo. The coexistence of alternative DNA conformations in living cells implies the potential of these structures or their transitions for important functions in genetic regulatory processes.

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Year:  1988        PMID: 3050986      PMCID: PMC282125          DOI: 10.1073/pnas.85.19.7069

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  26 in total

1.  Regulation of bacterial DNA supercoiling: plasmid linking numbers vary with growth temperature.

Authors:  E Goldstein; K Drlica
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

2.  The facile generation of covalently closed, circular DNAs with defined negative superhelical densities.

Authors:  C K Singleton; R D Wells
Journal:  Anal Biochem       Date:  1982-05-15       Impact factor: 3.365

3.  In Z-DNA the sequence G-C-G-C is neither methylated by Hha I methyltransferase nor cleaved by Hha I restriction endonuclease.

Authors:  L Vardimon; A Rich
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

4.  DNA structure and gene regulation.

Authors:  R D Wells; T C Goodman; W Hillen; G T Horn; R D Klein; J E Larson; U R Müller; S K Neuendorf; N Panayotatos; S M Stirdivant
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1980

5.  Energetics of B-to-Z transition in DNA.

Authors:  L J Peck; J C Wang
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

6.  Kinetics of methylation in Escherichia coli K-12.

Authors:  S M Lyons; P F Schendel
Journal:  J Bacteriol       Date:  1984-07       Impact factor: 3.490

7.  Energetic and structural inter-relationship between DNA supercoiling and the right- to left-handed Z helix transitions in recombinant plasmids.

Authors:  S M Stirdivant; J Kłysik; R D Wells
Journal:  J Biol Chem       Date:  1982-09-10       Impact factor: 5.157

8.  Facile transition of poly[d(TG) x d(CA)] into a left-handed helix in physiological conditions.

Authors:  D B Haniford; D E Pulleyblank
Journal:  Nature       Date:  1983-04-14       Impact factor: 49.962

9.  S1 nuclease recognizes DNA conformational junctions between left-handed helical (dT-dG n. dC-dA)n and contiguous right-handed sequences.

Authors:  C K Singleton; M W Kilpatrick; R D Wells
Journal:  J Biol Chem       Date:  1984-02-10       Impact factor: 5.157

10.  Conformational flexibility of junctions between contiguous B- and Z-DNAs in supercoiled plasmids.

Authors:  C K Singleton; J Klysik; R D Wells
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

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  26 in total

1.  Potassium permanganate as an in situ probe for B-Z and Z-Z junctions.

Authors:  H Jiang; W Zacharias; S Amirhaeri
Journal:  Nucleic Acids Res       Date:  1991-12-25       Impact factor: 16.971

2.  A potential Z-DNA-forming sequence is located between two transcription units alternatively expressed during development of Drosophila hydei.

Authors:  A Jimenez-Ruiz; J M Requena; M C Lopez; C Alonso
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-01       Impact factor: 11.205

3.  Surveying a supercoil domain by using the gamma delta resolution system in Salmonella typhimurium.

Authors:  N P Higgins; X Yang; Q Fu; J R Roth
Journal:  J Bacteriol       Date:  1996-05       Impact factor: 3.490

4.  Superhelical torsion in cellular DNA responds directly to environmental and genetic factors.

Authors:  J A McClellan; P Boublíková; E Palecek; D M Lilley
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

5.  Hyper-negative template DNA supercoiling during transcription of the tetracycline-resistance gene in topA mutants is largely constrained in vivo.

Authors:  A C Albert; F Spirito; N Figueroa-Bossi; L Bossi; A R Rahmouni
Journal:  Nucleic Acids Res       Date:  1996-08-01       Impact factor: 16.971

6.  How topoisomerase IV can efficiently unknot and decatenate negatively supercoiled DNA molecules without causing their torsional relaxation.

Authors:  Eric J Rawdon; Julien Dorier; Dusan Racko; Kenneth C Millett; Andrzej Stasiak
Journal:  Nucleic Acids Res       Date:  2016-04-22       Impact factor: 16.971

7.  Z-DNA-forming sequences are spontaneous deletion hot spots.

Authors:  A M Freund; M Bichara; R P Fuchs
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

8.  Molecular cloning of a Drosophila potential Z-DNA forming sequence hybridizing in situ to a developmentally regulated subdivision of the polytene chromosomes.

Authors:  A Jimenez-Ruiz; J M Requena; F Lancillotti; G Morales; M C Lopez; C Alonso
Journal:  Nucleic Acids Res       Date:  1989-06-26       Impact factor: 16.971

9.  Formation of (dA-dT)n cruciforms in Escherichia coli cells under different environmental conditions.

Authors:  A Dayn; S Malkhosyan; D Duzhy; V Lyamichev; Y Panchenko; S Mirkin
Journal:  J Bacteriol       Date:  1991-04       Impact factor: 3.490

10.  Intercalation of psoralen into DNA of plastid chromosomes decreases late during barley chloroplast development.

Authors:  J P Davies; R J Thompson; G Mosig
Journal:  Nucleic Acids Res       Date:  1991-10-11       Impact factor: 16.971

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