Literature DB >> 30507232

Reducing intrusive memories of trauma using a visuospatial interference intervention with inpatients with posttraumatic stress disorder (PTSD).

Henrik Kessler1, Emily A Holmes2, Simon E Blackwell3, Anna-Christine Schmidt1, Johanna M Schweer1, Anna Bücker1, Stephan Herpertz1, Nikolai Axmacher4, Aram Kehyayan1.   

Abstract

OBJECTIVE: The core clinical feature of posttraumatic stress disorder (PTSD) is recurrent intrusive memories of trauma. This study aimed to test a novel and simple intervention, inspired by the concepts of concurrent task interference and memory reconsolidation, to reduce the occurrence of intrusive memories among inpatients with complex PTSD.
METHOD: In this open-label single case series 20 patients with longstanding complex PTSD in inpatient treatment monitored the occurrence of intrusive trauma memories (intrusions) over the course of their admission (5 to 10 weeks). Patients received study-specific intervention sessions (including a memory reminder for a specific intrusion then 25 min Tetris gameplay) on a weekly basis. A within-subjects multiple baseline AB design was used, in that the length of baseline ("A," preintervention, monitoring only) and postintervention ("B") phases varied within-subjects across individual intrusions. Further, some intrusions were never targeted by the intervention. The study was registered prior to analysis, ISRCTN34320836.
RESULTS: Frequency of targeted intrusions reduced by on average 64% from baseline to the postintervention phase. Conversely, never-targeted intrusions reduced in frequency by on average 11% over a comparable time-period. Of the 20 patients, 16 met our criteria for showing "response" to the intervention.
CONCLUSIONS: Results provide initial evidence that this brief behavioral procedure might reduce the occurrence of intrusive traumatic memories in longstanding and complex PTSD, here delivered in an inpatient setting. The potential of this simple, focused intervention opens up new possibilities for tackling a core clinical symptom of PTSD, warranting further research. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

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Year:  2018        PMID: 30507232     DOI: 10.1037/ccp0000340

Source DB:  PubMed          Journal:  J Consult Clin Psychol        ISSN: 0022-006X


  16 in total

1.  Intrusive memories and voluntary memory of a trauma film: Differential effects of a cognitive interference task after encoding.

Authors:  Alex Lau-Zhu; Richard N Henson; Emily A Holmes
Journal:  J Exp Psychol Gen       Date:  2019-04-25

2.  Mobilum-a new mobile app to engage visuospatial processing for the reduction of intrusive visual memories.

Authors:  Henrik Kessler; Luisa Dangellia; Ralf Kessler; Vincent Mahnke; Stephan Herpertz; Aram Kehyayan
Journal:  Mhealth       Date:  2019-11-22

3.  Trauma, treatment and Tetris: video gaming increases hippocampal volume in male patients with combat-related posttraumatic stress disorder.

Authors:  Oisin Butler; Kerstin Herr; Gerd Willmund; Jürgen Gallinat; Simone Kühn; Peter Zimmermann
Journal:  J Psychiatry Neurosci       Date:  2020-07-01       Impact factor: 6.186

4.  Neuromodulation of Visual Cortex Reduces the Intensity of Intrusive Memories.

Authors:  Noa Herz; Yair Bar-Haim; Ido Tavor; Niv Tik; Haggai Sharon; Emily A Holmes; Nitzan Censor
Journal:  Cereb Cortex       Date:  2022-01-10       Impact factor: 5.357

5.  Arresting visuospatial stimulation is insufficient to disrupt analogue traumatic intrusions.

Authors:  Thomas Meyer; Chris R Brewin; John A King; Desiree Nijmeijer; Marcella L Woud; Eni S Becker
Journal:  PLoS One       Date:  2020-02-03       Impact factor: 3.240

6.  Reducing intrusive memories after trauma via a brief cognitive task intervention in the hospital emergency department: an exploratory pilot randomised controlled trial.

Authors:  Marie Kanstrup; Laura Singh; Katarina E Göransson; Julia Widoff; Rod S Taylor; Beau Gamble; Lalitha Iyadurai; Michelle L Moulds; Emily A Holmes
Journal:  Transl Psychiatry       Date:  2021-01-11       Impact factor: 6.222

7.  Bayesian Time-Series Models in Single Case Experimental Designs: A Tutorial for Trauma Researchers.

Authors:  Prathiba Natesan Batley; Ateka A Contractor; Stephanie V Caldas
Journal:  J Trauma Stress       Date:  2020-11-17

8.  Intrusive memories of trauma: A target for research bridging cognitive science and its clinical application.

Authors:  Lalitha Iyadurai; Renée M Visser; Alex Lau-Zhu; Kate Porcheret; Antje Horsch; Emily A Holmes; Ella L James
Journal:  Clin Psychol Rev       Date:  2018-08-23

9.  Emotional Mental Imagery Abnormalities in Monozygotic Twins With, at High-Risk of, and Without Affective Disorders: Present in Affected Twins in Remission but Absent in High-Risk Twins.

Authors:  Martina Di Simplicio; Alex Lau-Zhu; Iselin Meluken; Patrick Taylor; Lars Vedel Kessing; Maj Vinberg; Emily Alexandra Holmes; Kamilla Woznica Miskowiak
Journal:  Front Psychiatry       Date:  2019-11-08       Impact factor: 4.157

Review 10.  Fear not: recent advances in understanding the neural basis of fear memories and implications for treatment development.

Authors:  Amy L Milton
Journal:  F1000Res       Date:  2019-11-21
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