| Literature DB >> 30506188 |
Joe Leigh Simpson1,2,3, Anver Kuliev4,5, Svetlana Rechitsky4,5.
Abstract
Preimplantation genetic diagnosis (PGD) can be considered the earliest form of prenatal testing. It was first used in humans over 26 years ago. At its inception, PGD could only be performed for a limited number of genetic disorders. Technological advances in molecular biology and cytogenomics have been utilized in the field of PGD to greatly expand the spectrum of genetic disorders that can now be detected in early human embryos.Entities:
Keywords: Biopsy; Blastomere; Mosaicism; PGD; PGT; PGT-A; PGT-HLA; PGT-M; PGT-SR; Preimplantation genetic diagnosis; Single gene disorder; Trophectoderm
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Year: 2019 PMID： 30506188 DOI： 10.1007/978-1-4939-8889-1_2
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745