Literature DB >> 30502672

Evaluation of the sintering temperature on the mechanical behavior of β-tricalcium phosphate/calcium silicate scaffolds obtained by gelcasting method.

Lilian de Siqueira1, Cynthia Guimarães de Paula1, Rubia Figueredo Gouveia2, Mariana Motisuke1, Eliandra de Sousa Trichês3.   

Abstract

Scaffolds have been studied during the last decades as an alternative method to repair tissues. They are porous structures that act as a substrate for cellular growth, proliferation and differentiation. In this study, scaffolds of β-tricalcium phosphate with calcium silicate fibers were prepared by gel casting method in order to be characterized and validated as a better choice for bone tissue treatment. Gel-casting led to scaffolds with high porosity (84%) and pores sizes varying from 160 to 500 µm, which is an important factor for the neovascularization of the growing tissue. Biocompatible and bioactive calcium silicate fibers, which can be successfully produced by molten salt method, were added into the scaffolds as a manner to improve its mechanical resistance and bioactivity. The addition of 5 wt% of calcium silicate fibers associated with a higher sintering temperature (1300 °C) increased by 64.6% the compressive strength of the scaffold and it has also led to the formation of a dense and uniform apatite layer after biomineralization assessment.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Calcium silicate fibers; Gel casting method; Mechanical strength; Scaffolds; β-tricalcium phosphate

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Year:  2018        PMID: 30502672     DOI: 10.1016/j.jmbbm.2018.11.014

Source DB:  PubMed          Journal:  J Mech Behav Biomed Mater        ISSN: 1878-0180


  1 in total

1.  Cobalt-doped bioceramic scaffolds fabricated by 3D printing show enhanced osteogenic and angiogenic properties for bone repair.

Authors:  Jungang Li; Chaoqian Zhao; Chun Liu; Zhenyu Wang; Zeming Ling; Bin Lin; Bizhi Tan; Linquan Zhou; Yan Chen; Delong Liu; Xuenong Zou; Wenge Liu
Journal:  Biomed Eng Online       Date:  2021-07-24       Impact factor: 2.819

  1 in total

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