| Literature DB >> 30500530 |
Timothy J Welsh1, Yi Shen1, Aviad Levin1, Tuomas P J Knowles2.
Abstract
The use of optogenetic approaches has revealed new roles for intracellular protein condensates described in two papers in this issue of Cell (Bracha et. al., 2018; Shin et al., 2018). These results show that growing condensates are able to exert mechanical forces resulting in chromatin rearrangement, establishing a new role for liquid-liquid phase separation in the mechanobiology of the cell.Mesh：
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Year: 2018 PMID： 30500530 DOI： 10.1016/j.cell.2018.11.020
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582