X Chang1, P Song, M Wang, L An. 1. Lin An, Department of Maternal and Child Health, School of Public Health, Peking University, Beijing 100191, China, anlinbjmu@163.com.
Abstract
OBJECTIVE: Several studies have revealed that exposure to famine in early life was associated with higher body mass index(BMI) and waist circumference, and most of them used data from cross-sectional studies and defined those born before or after the famine period as non-exposed participants, which ignored the effects caused by age. Our objective was to study the effects of undernutrition in early life on overweight, obesity and abdominal obesity in those aged 54-56. METHODS: This was a retrospective cohort study with the status at age of 54-56 as outcomes. 1092 participants born between 1959 and 1961 from 2015 wave of China Health and Retirement Longitudinal Study (CHARLS) were defined as exposed and 1616 born between 1955 and 1957 from 2011 wave of CHARLS were defined as control. We used the prevalence odds ratios(ORs) to estimate the risks of overweight, obesity, abdominal obesity, and stratified by famine severity and sex separately for comparisons. RESULTS: Exposed group had higher risks of overweight (OR 1.357, 95%CI 1.067,1.727) and obesity (OR 1.356, 95%CI 1.001,1.836) in women, not in men. Participants in exposed group were more likely to have abdominal obesity (OR 1.362, 95%CI 1.139,1.629), regardless of famine severity and gender. CONCLUSION: Undernutrition in early life increased the risks of overweight and obesity in women not in men. And the risk of abdominal obesity was increased with the experience of undernutrition at early age both in men and women.
OBJECTIVE: Several studies have revealed that exposure to famine in early life was associated with higher body mass index(BMI) and waist circumference, and most of them used data from cross-sectional studies and defined those born before or after the famine period as non-exposed participants, which ignored the effects caused by age. Our objective was to study the effects of undernutrition in early life on overweight, obesity and abdominal obesity in those aged 54-56. METHODS: This was a retrospective cohort study with the status at age of 54-56 as outcomes. 1092 participants born between 1959 and 1961 from 2015 wave of China Health and Retirement Longitudinal Study (CHARLS) were defined as exposed and 1616 born between 1955 and 1957 from 2011 wave of CHARLS were defined as control. We used the prevalence odds ratios(ORs) to estimate the risks of overweight, obesity, abdominal obesity, and stratified by famine severity and sex separately for comparisons. RESULTS: Exposed group had higher risks of overweight (OR 1.357, 95%CI 1.067,1.727) and obesity (OR 1.356, 95%CI 1.001,1.836) in women, not in men. Participants in exposed group were more likely to have abdominal obesity (OR 1.362, 95%CI 1.139,1.629), regardless of famine severity and gender. CONCLUSION: Undernutrition in early life increased the risks of overweight and obesity in women not in men. And the risk of abdominal obesity was increased with the experience of undernutrition at early age both in men and women.
Authors: Zumin Shi; Stephen J Nicholls; Anne W Taylor; Dianna J Magliano; Sarah Appleton; Paul Zimmet Journal: J Hypertens Date: 2018-01 Impact factor: 4.844
Authors: M O Nielsen; A H Kongsted; M P Thygesen; A B Strathe; S Caddy; B Quistorff; W Jørgensen; V G Christensen; S Husted; A Chwalibog; K Sejrsen; S Purup; E Svalastoga; F J McEvoy; L Johnsen Journal: Br J Nutr Date: 2012-10-15 Impact factor: 3.718
Authors: Yanping Li; Vincent W Jaddoe; Lu Qi; Yuna He; Dong Wang; Jianqiang Lai; Jian Zhang; Ping Fu; Xiaoguang Yang; Frank B Hu Journal: Diabetes Care Date: 2011-02-10 Impact factor: 19.112
Authors: María Teresa Ramírez-López; Mariam Vázquez; Laura Bindila; Ermelinda Lomazzo; Clementine Hofmann; Rosarío Noemí Blanco; Francisco Alén; María Antón; Juan Decara; Rocío Arco; Daniel Ouro; Laura Orio; Juan Suárez; Beat Lutz; Raquel Gómez de Heras; Fernando Rodríguez de Fonseca Journal: Front Behav Neurosci Date: 2016-11-01 Impact factor: 3.558