Freerk T Baumann1, Alexandra Reike1, Michael Hallek1, Joachim Wiskemann2, Vanessa Reimer1. 1. Department I of Internal Medicine, Center of Integrated Oncology Cologne Bonn, University Hospital of Cologne, Cologne, Germany. 2. Department of Medical Oncology, National Center for Tumor Diseases (NCT), Heidelberg University Hospital, Heidelberg, Germany.
Abstract
BACKGROUND: Secondary lymphedema (SL) is a possible side effect of breast cancer treatment. Current data describe a positive influence of exercise on upper lymphedema. This systematic review evaluates studies examining a potential preventive effect of exercise on SL incidence. METHODS: A systematic literature search of PubMed, LIVIVO, and the Cochrane Library was performed. RESULTS: 8 randomized controlled trials were included in the review. 3 studies investigated the effect of strength training, and 5 the effect of combined exercise therapy. 5 studies included participants without lymphedema at study entry, and 3 studies included both patients with and without lymphedema. The partly significant results showed that progressive strength training as well as combined dynamic exercise therapies consisting of physiotherapy, physical therapy, and/or kinesiotherapy are safe and can prevent SL. Onset as well as diagnosis of lymphedema were significantly decreased in 5 studies in the exercise group. CONCLUSION: All 8 studies included indicate a potential preventive effect of exercise on SL; however, further research is needed.
BACKGROUND: Secondary lymphedema (SL) is a possible side effect of breast cancer treatment. Current data describe a positive influence of exercise on upper lymphedema. This systematic review evaluates studies examining a potential preventive effect of exercise on SL incidence. METHODS: A systematic literature search of PubMed, LIVIVO, and the Cochrane Library was performed. RESULTS: 8 randomized controlled trials were included in the review. 3 studies investigated the effect of strength training, and 5 the effect of combined exercise therapy. 5 studies included participants without lymphedema at study entry, and 3 studies included both patients with and without lymphedema. The partly significant results showed that progressive strength training as well as combined dynamic exercise therapies consisting of physiotherapy, physical therapy, and/or kinesiotherapy are safe and can prevent SL. Onset as well as diagnosis of lymphedema were significantly decreased in 5 studies in the exercise group. CONCLUSION: All 8 studies included indicate a potential preventive effect of exercise on SL; however, further research is needed.
Entities:
Keywords:
Breast cancer; Exercise; Lymphedema; Prevention; Prophylaxis
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