Nallan C Chaitanya1, Danam R Priyanka2, Nithika Madireddy2, Jampani N Priyanka2, Madathanapalle Ramakrishna3, Mujja Ajay4, Ancy V Ignatius2. 1. Department of Oral Medicine and Radiology, Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre Hyderabad, Telangana, India, Phone: +918374930914, e-mail: nallanchaitanya@gmail.com. 2. Department of Oral Medicine and Radiology, Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre Hyderabad, Telangana, India. 3. Department of Dentistry, Ministry of Health, Riyadh, Kingdom of Saudi Arabia. 4. Private Practitioner, Hyderabad, Telangana, India.
Abstract
AIM: To correlate the possible association between melasma, periodontitis, vitamin D abnormalities, and anemia. MATERIALS AND METHODS: A total of 192 subjects, of either gender within the age group of 30 to 70 years were divided equally into two groups, group I (case group, patients with melasma) and group II (control group, patients without melasma). In all the subjects, anemia and periodontitis were checked clinically, along with biochemical evaluation of serum vitamin D levels and hemoglobin (Hb) percentage. RESULTS: Student's t-test was performed with group statistics and chi-square for intervariable correlation was carried out. A significant correlation was found between patients having melasma and serum vitamin D levels with a p-value of 0.050. Between patients with melasma and periodontitis, there was a very significant correlation between the variables, with a p-value of 0.001. Conversely, the correlation between melasma and Hb percentage was found to be insignificant with the p-value 0.243, and all of the p-values remained at <0.05.The study thus demonstrated significant correlation between melasma, vitamin D abnormalities, and clinical periodontitis (p-value < 0.05), and no significant correlation between melasma and Hb. CONCLUSION: The cross-sectional study revealed that patients with melasma may have abnormal serum vitamin D and clinical periodontitis. This presence may be considered a syndromic occurrence. CLINICAL SIGNIFICANCE: The present study was done to correlate and also evaluate periodontitis, vitamin D abnormalities, and anemia in patients with melasma. It is primarily an observational study, attempting to evaluate the co-occurrence of the above-mentioned variables. The findings may prompt us to further investigate melasma for the presence of periodontitis, anemia, and vitamin D abnormalities.
AIM: To correlate the possible association between melasma, periodontitis, vitamin D abnormalities, and anemia. MATERIALS AND METHODS: A total of 192 subjects, of either gender within the age group of 30 to 70 years were divided equally into two groups, group I (case group, patients with melasma) and group II (control group, patients without melasma). In all the subjects, anemia and periodontitis were checked clinically, along with biochemical evaluation of serum vitamin D levels and hemoglobin (Hb) percentage. RESULTS: Student's t-test was performed with group statistics and chi-square for intervariable correlation was carried out. A significant correlation was found between patients having melasma and serum vitamin D levels with a p-value of 0.050. Between patients with melasma and periodontitis, there was a very significant correlation between the variables, with a p-value of 0.001. Conversely, the correlation between melasma and Hb percentage was found to be insignificant with the p-value 0.243, and all of the p-values remained at <0.05.The study thus demonstrated significant correlation between melasma, vitamin D abnormalities, and clinical periodontitis (p-value < 0.05), and no significant correlation between melasma and Hb. CONCLUSION: The cross-sectional study revealed that patients with melasma may have abnormal serum vitamin D and clinical periodontitis. This presence may be considered a syndromic occurrence. CLINICAL SIGNIFICANCE: The present study was done to correlate and also evaluate periodontitis, vitamin D abnormalities, and anemia in patients with melasma. It is primarily an observational study, attempting to evaluate the co-occurrence of the above-mentioned variables. The findings may prompt us to further investigate melasma for the presence of periodontitis, anemia, and vitamin D abnormalities.
Entities:
Keywords:
Hemoglobin percentage; Melasma; Periodontitis Vitamin D.