| Literature DB >> 30498040 |
Jemimah Ride1, Panagiotis Kasteridis1, Nils Gutacker1, Christoph Kronenberg2,3,4, Tim Doran5, Anne Mason1, Nigel Rice1, Hugh Gravelle1, Maria Goddard1, Tony Kendrick6, Najma Siddiqi5, Simon Gilbody5, Ceri Rj Dare7, Lauren Aylott7, Rachael Williams8, Rowena Jacobs1.
Abstract
OBJECTIVE: To investigate whether two primary care activities that are framed as indicators of primary care quality (comprehensive care plans and annual reviews of physical health) influence unplanned utilisation of hospital services for people with serious mental illness (SMI). DESIGN, SETTING, PARTICIPANTS: Retrospective observational cohort study using linked primary care and hospital records (Hospital Episode Statistics) for 5158 patients diagnosed with SMI between April 2006 and March 2014, who attended 213 primary care practices in England that contribute to the Clinical Practice Research Datalink GOLD database. OUTCOMES AND ANALYSIS: Cox survival models were used to estimate the associations between two primary care quality indicators (care plans and annual reviews of physical health) and the hazards of three types of unplanned hospital utilisation: presentation to accident and emergency departments (A&E), admission for SMI and admission for ambulatory care sensitive conditions (ACSC).Entities:
Keywords: data linkage; hospital utilisation; primary care; quality in health care; schizophrenia & psychotic disorders
Mesh:
Year: 2018 PMID: 30498040 PMCID: PMC6278786 DOI: 10.1136/bmjopen-2018-023135
Source DB: PubMed Journal: BMJ Open ISSN: 2044-6055 Impact factor: 2.692
Population characteristics: number and proportion of individuals in the sample, total person-years in the sample and proportion of total person-years
| Individuals | Mean person-years | |
| (% of total individuals) | (% of total person-years) | |
| Total sample | 5158 | 14 736 |
| Age at diagnosis | ||
| 18–35 | 1540 (30) | 4388 (30) |
| 36–45 | 1008 (20) | 3206 (22) |
| 46–55 | 736 (14) | 2356 (16) |
| 56–65 | 561 (11) | 1780 (12) |
| >65 | 1313 (25) | 2646 (18) |
| Index of multiple deprivation | ||
| Quintile 1 (least deprived) | 922 (18) | 2535 (18) |
| Quintile 2 | 980 (19) | 2709 (19) |
| Quintile 3 | 951 (18) | 2613 (18) |
| Quintile 4 | 1150 (22) | 3232 (22) |
| Quintile 5 (most deprived) | 1155 (23) | 3286 (23) |
| Gender | ||
| Male | 2430 (47) | 6767 (47) |
| Female | 2728 (53) | 7609 (53) |
| Ethnicity | ||
| White | 3791 (73) | 10 546 (73) |
| Black and minority ethnicities | 1367 (27) | 3830 (27) |
| Number of primary care contacts in year preceding diagnosis | ||
| 0–4 | 1143 (22) | 3393 (24) |
| 5–9 | 1341 (26) | 4032 (28) |
| 10–14 | 946 (18) | 2598 (18) |
| 15–19 | 618 (12) | 1619 (11) |
| ≥20 | 1110 (22) | 2735 (19%) |
| Number of hospital admissions in year preceding diagnosis | ||
| 0 | 2886 (56) | 8515 (59) |
| 1 | 1250 (24) | 3384 (23) |
| 2 | 544 (11) | 1385 (10) |
| 3 | 478 (9) | 1092 (8) |
| Number of Charlson Index comorbidities at time of diagnosis | ||
| 0 | 3047 (59) | 9049 (63) |
| 1 | 1384 (27) | 3908 (27) |
| 2 | 446 (9) | 948 (7) |
| 3 or more | 281 (5) | 471 (3) |
| Comorbid depression at time of diagnosis | ||
| History of depression | 3358 (65) | 9648 (67) |
| No recorded history of depression | 1800 (35) | 4728 (33) |
| Smoking status | ||
| Current or ex-smoker | 3960 (77) | 11 059 (77) |
| No recorded history of smoking | 1198 (23) | 3317 (23) |
| SMI diagnostic group | ||
| Schizophrenia and other psychoses | 2884 (56) | 7292 (51) |
| Bipolar disorder and affective psychoses | 2078 (40) | 6314 (44) |
| Both | 196 (4) | 770 (5) |
| Financial year of diagnosis | ||
| 2006/2007 | 617 (12) | 3205 (22) |
| 2007/2008 | 523 (10) | 2381 (17) |
| 2008/2009 | 573 (11) | 2269 (16) |
| 2009/10 | 619 (12) | 2084 (14) |
| 2010/2011 | 607 (12) | 1611 (11) |
| 2011/2012 | 734 (14) | 1528 (11) |
| 2012/2013 | 732 (14) | 969 (7) |
| 2013/2014 | 753 (15) | 330 (2) |
| Care plans (varying over time)* | ||
| Current care plan (in last 12 months) | 5692 (40) | |
| Expired care plan (more than 12 months ago) | 4004 (28) | |
| No care plan at all | 4680 (32) | |
| Annual reviews (varying over time)* | ||
| Current annual review (in last 12 months) | 8579 (60) | |
| No annual review in last 12 months | 5797 (40) | |
Patient characteristics are fixed at baseline (date of diagnosis) except for care quality indicators, which vary over the study period.
*The three care plans categories are mutually exclusive (as are the two annual review categories) so each person’s total time observed is the sum of these categories.
Descriptive statistics for survival analysis, by outcome
| Outcome | A&E presentation | SMI admission | ACSC admission |
| N individuals | 4446 | 5158 | 5158 |
| Mean years observed | 1.50 | 2.47 | 2.56 |
| N with outcome (% of sample) | 2213 (50%) | 562 (11%) | 528 (10%) |
| Mean years observed to outcome* | 1.08 | 1.20 | 1.68 |
| N (% of events) with outcome occurring: | |||
| within 12 months of CP (current CP) | 756 (36%) | 200 (35%) | 171 (32%) |
| >12 months since CP (expired CP) | 250 (11%) | 77 (14%) | 109 (21%) |
| with no CP | 1207 (54%) | 285 (51%) | 248 (47%) |
| within 12 months of AR (current AR) | 1024 (46%) | 263 (47%) | 301 (57%) |
| with no current annual in last 12 months | 1189 (54%) | 299 (53%) | 227 (43%) |
The period of observation is shorter in the outcome-specific samples than the full study observation period because the patient exits observation once the first outcome event occurs.
A&E presentation: Presentation of any cause to the accident and emergency department.
SMI admission: Inpatient admission with a primary diagnosis of serious mental illness (ICD-10 codes F20-F31).
ACSC admission: Inpatient admission with a diagnosis of an ambulatory care-sensitive condition (see online supplementary table 1 for a list of conditions).
*Mean years observed from diagnosis to outcome for those who experienced the outcome.
AR, annual review of physical health; CP, care plan.
Figure 1Association of care quality indicators with each outcome. ACSC, ambulatory care sensitive condition; AR, annual review of physical health; CP, care plan; SMI, severe mental illness.
Main model—full results with A&E presentation as the outcome
| Main model | |
| Current annual review | 0.962 (0.856 to 1.080) |
| Current care plan | 0.866* (0.766 to 0.979) |
| Expired care plan | 0.808* (0.672 to 0.972) |
| Age at diagnosis | |
| 18 to 35 (base) | |
| 36 to 45 | 0.806* (0.657 to 0.988) |
| 46 to 55 | 0.619*** (0.507 to 0.755) |
| 56 to 65 | 0.582*** (0.460 to 0.738) |
| ≥66 | 1.098 (0.917 to 1.314) |
| Male | 1.016 (0.861 to 1.199) |
| Age at diagnosis *Male | |
| 18 to 35*Male (base) | |
| 36 to 45*Male | 0.919 (0.694 to 1.216) |
| 46 to 55*Male | 1.215 (0.911 to 1.614) |
| 56 to 65*Male | 1.432* (1.037 to 1.978) |
| ≥66*Male | 0.939 (0.727 to 1.203) |
| SMI diagnosis group | |
| Bipolar disorder or affective psychosis (base) | |
| Schizophrenia or other psychosis | 1.103 (0.997 to 1.220) |
| Both | 1.119 (0.888 to 1.411) |
| Index of Multiple Deprivation | |
| 1st quintile (base) | |
| 2nd quintile | 0.955 (0.804 to 1.133) |
| 3rd quintile | 1.100 (0.918 to 1.319) |
| 4th quintile | 1.178 (0.978 to 1.419) |
| 5th quintile | 1.196 (0.985 to 1.453) |
| Ethnicity white | 1.277*** (1.149 to 1.421) |
| Number of admissions within 12 months prior to diagnosis | |
| 0 (base) | |
| 1 | 1.174** (1.050 to 1.313) |
| 2 | 1.190* (1.028 to 1.377) |
| 3 or more | 1.500*** (1.268 to 1.775) |
| Number of primary care contacts within 12 months prior to diagnosis | |
| <5 (base) | |
| 5 to 9 | 1.219** (1.056 to 1.407) |
| 10 to 14 | 1.334*** (1.165 to 1.528) |
| 15 to 19 | 1.714*** (1.459 to 2.013) |
| ≥20 | 1.861*** (1.592 to 2.176) |
| Current or ex-smoker | 1.101 (0.983 to 1.233) |
| Number of Charlson Index comorbidities | 1.111*** (1.052 to 1.174) |
| Diagnosis of depression | 1.005 (0.904 to 1.118) |
| Year of diagnosis | |
| 2007 (base) | |
| 2008 | 1.263* (1.040 to 1.532) |
| 2009 | 1.383*** (1.149 to 1.665) |
| 2010 | 1.644*** (1.356 to 1.994) |
| 2011 | 1.551*** (1.244 to 1.933) |
| 2012 | 1.385** (1.105 to 1.737) |
| 2013 | 1.266 (0.990 to 1.614) |
| 2014 | 0.970 (0.557 to 1.691) |
| Practice list size | 1.000 (1.000 to 1.000) |
| Number of patients | 4446 |
*p<0.05, **p<0.01, ***p<0.001.
SMI, severe mental illness.