Hilde Tinderholt Myrhaug1, Julia Aneth Mbalilaki2, Nataskja-Elena Kersting Lie3, Tone Hansen4, Jan Egil Nordvik2. 1. Division of Health Services, Norwegian Institute of Public Health, Oslo, Norway. 2. Regional Knowledge Translation Center, Southern-Eastern Norway Regional Health Authority, Sunnaas Rehabilitation Hospital, Oslo, Norway. 3. Institute of Physiotherapy, Oslo and Akershus University College of Applied Sciences, Oslo, Norway. 4. The Norwegian Leukemia Association, Oslo, Norway.
Abstract
Purpose: To summarize evidence on the effects of multidisciplinary psychosocial rehabilitation interventions for adult cancer patients on fatigue, quality of life, participation, coping, and self-efficacy.Materials and methods: We searched MEDLINE, Embase, PyscINFO, PEDro, OT Seeker, Sociological Abstracts, CINAHL, and Cochrane CENTRAL for randomized controlled trials. Two reviewers selected articles independently. Results: Thirty-one articles were included and four meta-analyses were conducted. The results of one meta-analysis was statistically significant when comparing multidisciplinary psychosocial interventions to standard care on fatigue among breast cancer patients (standardized mean differences [SMD] 0.30 (95% confidence interval [CI] 0.04, 0.56)) at 2-6 months follow-up. However, no significant results were revealed on health-related quality of life among breast cancer (SMD 0.38 (95% CI -0.40, 1.16)), prostate cancer (SMD 0.06 (95% CI -0.18, 0.29)), and patients with different cancer diagnoses (SMD 0.06 (95% CI -0.14, 0.25)) at follow-up. One study reported on effects of interventions on participation, and four studied the outcomes of coping and self-efficacy.Conclusions: Multidisciplinary psychosocial interventions may decrease fatigue among breast cancer patients. There is an urgent need for rigorous designed trials in cancer rehabilitation, preferably on fatigue, participation, and coping or self-efficacy. The interventions need to be thoroughly described.Implications for rehabilitationMultidisciplinary psychosocial interventions may reduce fatigue among breast cancer patients.The effects of multidisciplinary psychosocial interventions among cancer patients on health-related quality of life, participation, and coping are unclear.Urgent need for a systemic approach to the development and conduction of multidisciplinary psychosocial interventions, ideally based on guidelines for complex interventions.Need of larger and more rigorously conducted randomized controlled trials investigating the effects of these rehabilitation interventions on fatigue, participation and coping.
Purpose: To summarize evidence on the effects of multidisciplinary psychosocial rehabilitation interventions for adult cancerpatients on fatigue, quality of life, participation, coping, and self-efficacy.Materials and methods: We searched MEDLINE, Embase, PyscINFO, PEDro, OT Seeker, Sociological Abstracts, CINAHL, and Cochrane CENTRAL for randomized controlled trials. Two reviewers selected articles independently. Results: Thirty-one articles were included and four meta-analyses were conducted. The results of one meta-analysis was statistically significant when comparing multidisciplinary psychosocial interventions to standard care on fatigue among breast cancerpatients (standardized mean differences [SMD] 0.30 (95% confidence interval [CI] 0.04, 0.56)) at 2-6 months follow-up. However, no significant results were revealed on health-related quality of life among breast cancer (SMD 0.38 (95% CI -0.40, 1.16)), prostate cancer (SMD 0.06 (95% CI -0.18, 0.29)), and patients with different cancer diagnoses (SMD 0.06 (95% CI -0.14, 0.25)) at follow-up. One study reported on effects of interventions on participation, and four studied the outcomes of coping and self-efficacy.Conclusions: Multidisciplinary psychosocial interventions may decrease fatigue among breast cancerpatients. There is an urgent need for rigorous designed trials in cancer rehabilitation, preferably on fatigue, participation, and coping or self-efficacy. The interventions need to be thoroughly described.Implications for rehabilitationMultidisciplinary psychosocial interventions may reduce fatigue among breast cancerpatients.The effects of multidisciplinary psychosocial interventions among cancerpatients on health-related quality of life, participation, and coping are unclear.Urgent need for a systemic approach to the development and conduction of multidisciplinary psychosocial interventions, ideally based on guidelines for complex interventions.Need of larger and more rigorously conducted randomized controlled trials investigating the effects of these rehabilitation interventions on fatigue, participation and coping.
Authors: Michael Kusch; Hildegard Labouvie; Vera Schiewer; Natalie Talalaev; Jan C Cwik; Sonja Bussmann; Lusine Vaganian; Alexander L Gerlach; Antje Dresen; Natalia Cecon; Sandra Salm; Theresia Krieger; Holger Pfaff; Clarissa Lemmen; Lisa Derendorf; Stephanie Stock; Christina Samel; Anna Hagemeier; Martin Hellmich; Bernd Leicher; Gregor Hültenschmidt; Jessica Swoboda; Peter Haas; Anna Arning; Andrea Göttel; Kathrin Schwickerath; Ullrich Graeven; Stefanie Houwaart; Hedy Kerek-Bodden; Steffen Krebs; Christiana Muth; Christina Hecker; Marcel Reiser; Cornelia Mauch; Jennifer Benner; Gerdamarie Schmidt; Christiane Karlowsky; Gisela Vimalanandan; Lukas Matyschik; Lars Galonska; Annette Francke; Karin Osborne; Ursula Nestle; Markus Bäumer; Kordula Schmitz; Jürgen Wolf; Michael Hallek Journal: BMC Health Serv Res Date: 2022-04-22 Impact factor: 2.908