Literature DB >> 30483683

Continuous flow chemistry: where are we now? Recent applications, challenges and limitations.

Faith M Akwi1, Paul Watts.   

Abstract

A general outlook of the changing face of chemical synthesis is provided in this article through recent applications of continuous flow processing in both industry and academia. The benefits, major challenges and limitations associated with the use of this mode of processing are also given due attention as an attempt to put into perspective the current position of continuous flow processing, either as an alternative or potential combinatory technology for batch processing.

Year:  2018        PMID: 30483683     DOI: 10.1039/c8cc07427e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  18 in total

Review 1.  Technological Innovations in Photochemistry for Organic Synthesis: Flow Chemistry, High-Throughput Experimentation, Scale-up, and Photoelectrochemistry.

Authors:  Laura Buglioni; Fabian Raymenants; Aidan Slattery; Stefan D A Zondag; Timothy Noël
Journal:  Chem Rev       Date:  2021-08-10       Impact factor: 60.622

Review 2.  Greening the synthesis of peptide therapeutics: an industrial perspective.

Authors:  Vincent Martin; Peter H G Egelund; Henrik Johansson; Sebastian Thordal Le Quement; Felix Wojcik; Daniel Sejer Pedersen
Journal:  RSC Adv       Date:  2020-11-24       Impact factor: 4.036

Review 3.  3D printing and continuous flow chemistry technology to advance pharmaceutical manufacturing in developing countries.

Authors:  Cloudius R Sagandira; Margaret Siyawamwaya; Paul Watts
Journal:  Arab J Chem       Date:  2020-09-23       Impact factor: 5.165

4.  Kinetics Studies on a Multicomponent Knoevenagel-Michael Domino Reaction by an Automated Flow Reactor.

Authors:  Christian P Haas; Ulrich Tallarek
Journal:  ChemistryOpen       Date:  2019-04-29       Impact factor: 2.911

5.  Catalyst shuttling enabled by a thermoresponsive polymeric ligand: facilitating efficient cross-couplings with continuously recyclable ppm levels of palladium.

Authors:  Erfei Wang; Mao Chen
Journal:  Chem Sci       Date:  2019-07-23       Impact factor: 9.825

6.  Facile synthesis of supported Ru-Triphos catalysts for continuous flow application in selective nitrile reduction.

Authors:  Robert Konrath; Frank J L Heutz; Norbert Steinfeldt; Nils Rockstroh; Paul C J Kamer
Journal:  Chem Sci       Date:  2019-07-23       Impact factor: 9.825

7.  Amine-Functionalized Nanoporous Silica Monoliths for Heterogeneous Catalysis of the Knoevenagel Condensation in Flow.

Authors:  Kevin Turke; Rafael Meinusch; Pascal Cop; Eric Prates da Costa; Raoul D Brand; Anja Henss; Peter R Schreiner; Bernd M Smarsly
Journal:  ACS Omega       Date:  2020-12-21

Review 8.  Digitising chemical synthesis in automated and robotic flow.

Authors:  Tomas Hardwick; Nisar Ahmed
Journal:  Chem Sci       Date:  2020-10-07       Impact factor: 9.825

Review 9.  The evolution of Tamiflu synthesis, 20 years on: Advent of enabling technologies the last piece of the puzzle?

Authors:  Cloudius R Sagandira; Francis M Mathe; Upenyu Guyo; Paul Watts
Journal:  Tetrahedron       Date:  2020-07-26       Impact factor: 2.457

10.  3D-printed automation for optimized PET radiochemistry.

Authors:  Alejandro Amor-Coarasa; James M Kelly; John W Babich
Journal:  Sci Adv       Date:  2019-09-13       Impact factor: 14.136

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