| Literature DB >> 30482698 |
Jae-Hoon Ko1, Dong Sik Jung2, Ji Yeon Lee3, Hyun Ah Kim3, Seong Yeol Ryu3, Sook-In Jung4, Eun-Jeong Joo5, Shinhye Cheon6, Yeon-Sook Kim6, Shin-Woo Kim7, Sun Young Cho1, Cheol-In Kang1, Doo Ryeon Chung1, Nam Yong Lee8, Kyong Ran Peck9.
Abstract
An epidemiologic surveillance of non-albicans candidemia for a 6-year period was conducted in Korea. Compared to the published epidemiologic data for the previous 6 years, an increase of C. glabrata (from 21.3% to 28.5%) and a decrease of C. parapsilosis (from 36.5% to 24.7%) were noticed. During the study period, C. tropicalis (36.4%) was most frequently isolated non-albicans Candida, followed by C. glabrata (28.5%), C. parapsilosis (24.7%), and C. krusei (2.6%). Replacement of primary amphotericin B treatment with echinocandins (P < 0.001) eliminated amphotericin B resistance (from 7.8% in 2011 to 0% in 2014).Entities:
Keywords: Antifungal resistance; Candida glabrata; Candida parapsilosis; Epidemiology; non-albicans Candida
Mesh：
Substances：
Year: 2018 PMID： 30482698 DOI： 10.1016/j.jiac.2018.09.016
Source DB: PubMed Journal: J Infect Chemother ISSN： 1341-321X Impact factor: 2.211