Literature DB >> 3048259

Amyloid fibrils formed from a segment of the pancreatic islet amyloid protein.

G G Glenner1, E D Eanes, C A Wiley.   

Abstract

A synthetic peptide formed from residues 20-29 of the pancreatic islet amyloid protein has the confirmation of a twisted beta-pleated sheet protein suggesting it is a potential contributor toward amyloid fibril formation in the islets of Langerhans in Type 2 diabetes mellitus.

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Year:  1988        PMID： 3048259     DOI： 10.1016/s0006-291x(88)80538-2

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  32 in total

1.  Low levels of asparagine deamidation can have a dramatic effect on aggregation of amyloidogenic peptides: implications for the study of amyloid formation.

Authors:  Melanie R Nilsson; Miles Driscoll; Daniel P Raleigh
Journal:  Protein Sci       Date:  2002-02       Impact factor: 6.725

Review 2.  Islet amyloid polypeptide--a novel controversy in diabetes research.

Authors:  P Westermark; K H Johnson; T D O'Brien; C Betsholtz
Journal:  Diabetologia       Date:  1992-04       Impact factor: 10.122

3.  Beta structure motifs of islet amyloid polypeptides identified through surface-mediated assemblies.

Authors:  Xiao-Bo Mao; Chen-Xuan Wang; Xing-Kui Wu; Xiao-Jing Ma; Lei Liu; Lan Zhang; Lin Niu; Yuan-Yuan Guo; Deng-Hua Li; Yan-Lian Yang; Chen Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2011-11-21       Impact factor: 11.205

4.  Design and Optimization of Anti-amyloid Domain Antibodies Specific for β-Amyloid and Islet Amyloid Polypeptide.

Authors:  Christine C Lee; Mark C Julian; Kathryn E Tiller; Fanling Meng; Sarah E DuConge; Rehana Akter; Daniel P Raleigh; Peter M Tessier
Journal:  J Biol Chem       Date:  2015-11-24       Impact factor: 5.157

5.  Solution state structures of human pancreatic amylin and pramlintide.

Authors:  John R Cort; Zhihong Liu; Gregory M Lee; K N L Huggins; Susan Janes; Kathryn Prickett; Niels H Andersen
Journal:  Protein Eng Des Sel       Date:  2009-07-12       Impact factor: 1.650

6.  Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation.

Authors:  P Westermark; U Engström; K H Johnson; G T Westermark; C Betsholtz
Journal:  Proc Natl Acad Sci U S A       Date:  1990-07       Impact factor: 11.205

7.  Mechanism of IAPP amyloid fibril formation involves an intermediate with a transient β-sheet.

Authors:  Lauren E Buchanan; Emily B Dunkelberger; Huong Q Tran; Pin-Nan Cheng; Chi-Cheng Chiu; Ping Cao; Daniel P Raleigh; Juan J de Pablo; James S Nowick; Martin T Zanni
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-11       Impact factor: 11.205

8.  Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone.

Authors:  M Nishi; S J Chan; S Nagamatsu; G I Bell; D F Steiner
Journal:  Proc Natl Acad Sci U S A       Date:  1989-08       Impact factor: 11.205

9.  Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro.

Authors:  F Tagliavini; F Prelli; L Verga; G Giaccone; R Sarma; P Gorevic; B Ghetti; F Passerini; E Ghibaudi; G Forloni
Journal:  Proc Natl Acad Sci U S A       Date:  1993-10-15       Impact factor: 11.205

10.  Amyloidogenesis abolished by proline substitutions but enhanced by lipid binding.

Authors:  Ping Jiang; Weixin Xu; Yuguang Mu
Journal:  PLoS Comput Biol       Date:  2009-04-10       Impact factor: 4.475
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