Eun Nam Lee1, Moon Ja Kim2. 1. Department of Nursing, Dong-A University, Busan, Republic of Korea. 2. Department of Nursing, Dong-A University, Busan, Republic of Korea. Electronic address: moonja0503@gmail.com.
Abstract
PURPOSE: Pulmonary rehabilitation (PR) programs are important in the treatment of patients with chronic obstructive pulmonary disease (COPD) but vary widely in type, duration, and efficacy. This meta-analysis investigated the effect of PR programs on respiratory muscle strength in patients with COPD. METHODS: PubMed, Embase, and CINAHL were searched. The primary outcome variables were maximal expiratory pressure (MEP) and maximal inspiratory pressure (MIP). The secondary outcome variables were the modified Borg score after the 6-min walking test, percent predicted forced expiratory volume in 1 second (FEV1%pred), and percent FEV1/forced volume capacity (FVC). Comprehensive Meta-Analysis, version 3.0, was used to analyze the data. The effect size was calculated using the standardized mean difference (SMD) and 95% confidence interval (CI). RESULTS: Twenty randomized controlled trials (with 992 participants) were included in the analysis. The PR programs had a significant effect on the MEP (SMD, 0.87; 95% CI, 0.42-1.32; p < .001), MIP (SMD, 0.53; 95% CI, 0.13-0.93; p = .009), and modified Borg score (SMD, -0.37; 95% CI, -0.52 to -0.22; p < .001) in patients with COPD. There was no effect on FEV1%pred (SMD, 0.09; 95% CI, -0.12 to 0.30; p = .406) or FEV1/FVC% (SMD, 0.04; 95% CI, -0.17 to 0.26; p = .702). CONCLUSION: PR programs improve respiratory muscle strength in patients with COPD. Strategies for selecting a suitable PR program need to be developed, and future studies should evaluate the long-term effects of such programs on pulmonary function.
PURPOSE: Pulmonary rehabilitation (PR) programs are important in the treatment of patients with chronic obstructive pulmonary disease (COPD) but vary widely in type, duration, and efficacy. This meta-analysis investigated the effect of PR programs on respiratory muscle strength in patients with COPD. METHODS: PubMed, Embase, and CINAHL were searched. The primary outcome variables were maximal expiratory pressure (MEP) and maximal inspiratory pressure (MIP). The secondary outcome variables were the modified Borg score after the 6-min walking test, percent predicted forced expiratory volume in 1 second (FEV1%pred), and percent FEV1/forced volume capacity (FVC). Comprehensive Meta-Analysis, version 3.0, was used to analyze the data. The effect size was calculated using the standardized mean difference (SMD) and 95% confidence interval (CI). RESULTS: Twenty randomized controlled trials (with 992 participants) were included in the analysis. The PR programs had a significant effect on the MEP (SMD, 0.87; 95% CI, 0.42-1.32; p < .001), MIP (SMD, 0.53; 95% CI, 0.13-0.93; p = .009), and modified Borg score (SMD, -0.37; 95% CI, -0.52 to -0.22; p < .001) in patients with COPD. There was no effect on FEV1%pred (SMD, 0.09; 95% CI, -0.12 to 0.30; p = .406) or FEV1/FVC% (SMD, 0.04; 95% CI, -0.17 to 0.26; p = .702). CONCLUSION: PR programs improve respiratory muscle strength in patients with COPD. Strategies for selecting a suitable PR program need to be developed, and future studies should evaluate the long-term effects of such programs on pulmonary function.
Authors: Adam Lewis; Keir Elmslie James Philip; Adam Lound; Phoene Cave; Juliet Russell; Nicholas S Hopkinson Journal: BMJ Open Respir Res Date: 2021-11
Authors: Bruna T S Araújo; Ana Eugênia V R Barros; Daiara T X Nunes; Maria Inês Remígio de Aguiar; Viviane W Mastroianni; Juliana A F de Souza; Juliana Fernades; Shirley Lima Campos; Daniella Cunha Brandão; Armele Dornelas de Andrade Journal: Physiother Res Int Date: 2022-09-11