| Literature DB >> 30480457 |
Junrong Huang1, Wenli Bao1, Shuangping Huang1, Wei Yang1, Zhu Lizhi1, Guangyan Du1, Chi-Sing Lee1,2,3.
Abstract
A concise formal synthesis of (+)-phomactin A has been achieved. The key features of this synthetic strategy involve a one-pot Prins/Conia-ene cyclization protocol for the construction of the highly functionalized 1-oxadeclin core (AB ring) and a late-stage direct γ-hydroxylation of enone for the installation of the C ring.Entities:
Year: 2018 PMID： 30480457 DOI： 10.1021/acs.orglett.8b03242
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005