Resolution of Photoreceptor Layer Damage in Multiple Evanescent White Dot Syndrome.

PRESENTATION

Here, we present a case of multiple evanescent white dot syndrome (MEWDS) in which the photoreceptor degeneration was observed to have completely resolved at one year follow-up with reestablishment of the normal outer retina anatomy.

DISCUSSION

Multiple evanescent white dot syndrome (MEWDS) is an acute-onset chorioretinal inflammatory disease characterized by unilateral multiple gray-white dots of the posterior pole in young healthy women.[1] Both the symptoms (usually blurred vision and photopsia) and clinical signs of the disease are transient with complete recovery in most cases. Complications, as well as recurrence, are rare. The clinical signs include deep outer retinal yellow-white lesions that are 100–200 μm in size and foveal granularity.[2] Fourier-domain optical coherence tomography (OCT) localizes the visually significant changes observed in this disease at the level of the photoreceptors [Figure 1a]. These transient retinal changes specifically occur at the level of the inner segment ellipsoid and outer segment/retinal pigment epithelium line. OCT may show recovery of acute macular findings during the course of the disease with resolution of the inner segment/outer segment disruption [Figure 1b].[134]

Figure 1

(a) Acute optical coherence tomography features of multiple evanescent white dot syndrome in a 27-year-old woman who presented with complaints of blurred vision in the left eye. (b) One year later, optical coherence tomography showed reestablishment of the normal outer retina anatomy.

Financial Support and Sponsorship

Nil.

Conflicts of Interest

There are no conflicts of interest.