Literature DB >> 30479234

[From carbonmonoxide intoxication to organ donation; organ protective mechanic ventilation in severe pulmonary damage].

Mehtap Pehlivanlar Küçük1, Nazan Köylü İlkaya1, Çağatay Erman Öztürk1, Halil Cebeci1, Davut Aydın1, Fatma Ülger1.   

Abstract

Organ donation is a matter of concern in critically ill patients who need intensive care after carbonmonoxide (CO) intoxication. A 26-year-old female patient was unconscious after having spent 20 minutes in the bathroom with a water heater (70% butane and 30% propane mixture). In the CT of the patient with Glasgow Coma Scale (GCS) 3, ventricular system was erased, white-gray matter separation was lost and fissures were observed as erased. Torax CT showed conspicuous areas showing air bronchograms in both lung bases and posterior areas and diffuse frosted glass densities in other areas. In a patient with no improvement in consciousness; apnea test, neurological examination and CT angiography showed that there was no blood flow in the brain and brain death was confirmed. On the second day of hospitalization, the relatives gave their approval for the donation. It may also be advantageous to use oxygen at high concentrations in carbonmonoxide poisoning as it may allow recruitment of closed alveoli. Successful kidney, heart, lung, liver and pancreas transplants from donors exposed to CO have been reported. Carbonmonoxide intoxication may be appropriate for transplantation for patients who are waiting for organs of brain death cases where the organ preservation is well done. Although carbonmonoxide intoxication has failed in the literature, it shows that there is no definite contraindication.

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Year:  2018        PMID: 30479234     DOI: 10.5578/tt.67100

Source DB:  PubMed          Journal:  Tuberk Toraks        ISSN: 0494-1373


  1 in total

1.  Successful Multiorgan Donation From a Brain-dead Donor Following Liquid Nicotine Voluntary Intoxication: A Case Report.

Authors:  Ana M Domínguez-Berrot; Myriam González-Vaquero; Antonio Sánchez-Vallejo
Journal:  Transplant Direct       Date:  2021-05-18
  1 in total

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