Literature DB >> 30479009

The use of electrochemotherapy in combination with immunotherapy in the treatment of metastatic melanoma: a focused review.

Clare A Goggins1, Amor Khachemoune2.   

Abstract

Electrochemotherapy (ECT) is a treatment modality that combines low-dose chemotherapy with electroporation, thereby enhancing cytotoxicity. ECT was first utilized in the treatment of metastatic head and neck cancer. Today it is used as a local treatment for the cutaneous and subcutaneous metastases of a variety of cancers, including melanoma. In addition, recent evidence indicates that ECT in combination with immunotherapy can lead to a systemic tumor response. This review aims to summarize the efficacy of ECT in the treatment of metastatic melanoma, with a specific focus on the combination of ECT with immunotherapy.
© 2018 The International Society of Dermatology.

Entities:  

Keywords:  cutaneous metastases; electrochemotherapy; immunotherapy; melanoma

Year:  2018        PMID： 30479009     DOI： 10.1111/ijd.14314

Source DB:  PubMed          Journal:  Int J Dermatol        ISSN： 0011-9059            Impact factor:   2.736


  7 in total

Review 1.  Electroporation and Immunotherapy-Unleashing the Abscopal Effect.

Authors:  Tobias Freyberg Justesen; Adile Orhan; Hans Raskov; Christian Nolsoe; Ismail Gögenur
Journal:  Cancers (Basel)       Date:  2022-06-10       Impact factor: 6.575

2.  Emerging medical applications based on non-ionizing electromagnetic fields from 0 Hz to 10 THz.

Authors:  Mats-Olof Mattsson; Myrtill Simkó
Journal:  Med Devices (Auckl)       Date:  2019-09-12

3.  Bleomycin electrochemotherapy for the management of locally advanced metastatic melanoma: Two notable clinical cases potentially indicating a greater therapeutic role in the era of targeted and immuno-therapy.

Authors:  Michael Gallagher; Kuen Yeow Chin; Alastair MacKenzie-Ross
Journal:  JPRAS Open       Date:  2020-10-06

4.  Apoptotic mechanism activated by blue light and cisplatinum in cutaneous squamous cell carcinoma cells.

Authors:  Maria Fiorella Tartaglione; María Eléxpuru Zabaleta; Raffaella Lazzarini; Francesco Piva; Elena Marinelli Busilacchi; Antonella Poloni; Caterina Ledda; Venerando Rapisarda; Lory Santarelli; Massimo Bracci
Journal:  Int J Mol Med       Date:  2021-02-12       Impact factor: 4.101

Review 5.  Electrical Stimulation for Immune Modulation in Cancer Treatments.

Authors:  Ritopa Das; Sofia Langou; Thinh T Le; Pooja Prasad; Feng Lin; Thanh D Nguyen
Journal:  Front Bioeng Biotechnol       Date:  2022-01-11

6.  Electrochemotherapy as a Trigger to Overcome Primary Resistance to Anti-PD-1 Treatment: A Case Report of Melanoma of the Scalp.

Authors:  Davide Quaresmini; Alessandra Di Lauro; Livia Fucci; Sabino Strippoli; Ivana De Risi; Angela Monica Sciacovelli; Anna Albano; Gaetano Achille; Massimo Montepara; Sabino Russo; Gabriella Tassone; Michele Guida
Journal:  Front Oncol       Date:  2021-09-16       Impact factor: 6.244

Review 7.  Electrochemotherapy of skin metastases from malignant melanoma: a PRISMA-compliant systematic review.

Authors:  Luca Tagliaferri; Alessio G Morganti; Martina Ferioli; Valentina Lancellotta; Anna Myriam Perrone; Alessandra Arcelli; Andrea Galuppi; Lidia Strigari; Milly Buwenge; Francesca De Terlizzi; Silvia Cammelli; Roberto Iezzi; Pierandrea De Iaco
Journal:  Clin Exp Metastasis       Date:  2022-07-22       Impact factor: 4.510
  7 in total

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