Madhav K Manoj1, Roopesh Ramakrishnan2, Sujith Babjee2, Rasha Nasim2. 1. Department of Orthodontics and Dento-facial Orthopedics, PMS College of Dental Science and Research, Trivandrum, Kerala, India. Electronic address: madhavmanoj@gmail.com. 2. Department of Orthodontics and Dento-facial Orthopedics, PMS College of Dental Science and Research, Trivandrum, Kerala, India.
Abstract
INTRODUCTION: Our objective was to assess the levels of bisphenol A (BPA) released from light-cured and chemically cured resins used for orthodontic bracket bonding in 1 month. METHODS: Saliva specimens were obtained at 5 time periods from 40 healthy patients treated with orthodontic mechanotherapeutics. The periods of collections were just before bonding orthodontic brackets, followed by 30 minutes, 1 day, 1 week, and 1 month after orthodontic bonding. The specimens were analyzed with the high-performance liquid chromatography/mass spectrometry method for quantitative evaluation of BPA levels. RESULTS: We observed a large increase in BPA levels 30 minutes after orthodontic bonding in the 2 groups. Thereafter, there was sudden decline in BPA levels as time passed, and the levels reached a statistically significant level at 1 month after orthodontic bonding. Interestingly, the amount of BPA released from chemically cured resin was much higher; this was also significant statistically compared with light-cured resins. CONCLUSIONS: The results of this in-vivo approach with high-performance liquid chromatography on salivary specimens confirmed continued release of BPA after bonding brackets for 1 month, although in smaller quantities. The release during the initial 30 minutes is high, making it essential to introduce measures to dilute it for better patient safety.
INTRODUCTION: Our objective was to assess the levels of bisphenol A (BPA) released from light-cured and chemically cured resins used for orthodontic bracket bonding in 1 month. METHODS: Saliva specimens were obtained at 5 time periods from 40 healthy patients treated with orthodontic mechanotherapeutics. The periods of collections were just before bonding orthodontic brackets, followed by 30 minutes, 1 day, 1 week, and 1 month after orthodontic bonding. The specimens were analyzed with the high-performance liquid chromatography/mass spectrometry method for quantitative evaluation of BPA levels. RESULTS: We observed a large increase in BPA levels 30 minutes after orthodontic bonding in the 2 groups. Thereafter, there was sudden decline in BPA levels as time passed, and the levels reached a statistically significant level at 1 month after orthodontic bonding. Interestingly, the amount of BPA released from chemically cured resin was much higher; this was also significant statistically compared with light-cured resins. CONCLUSIONS: The results of this in-vivo approach with high-performance liquid chromatography on salivary specimens confirmed continued release of BPA after bonding brackets for 1 month, although in smaller quantities. The release during the initial 30 minutes is high, making it essential to introduce measures to dilute it for better patient safety.
Authors: Anabela Baptista Paula; Debbie Toste; Alfredo Marinho; Inês Amaro; Carlos-Miguel Marto; Ana Coelho; Manuel Marques-Ferreira; Eunice Carrilho Journal: Int J Environ Res Public Health Date: 2019-05-09 Impact factor: 3.390