| Literature DB >> 30477402 |
M Manasa1, P Revathi1, M Prudhvi Chand1, V Maroudam2, P Navaneetha1, G Dhinakar Raj2, P B Kavi Kishor1, B De3, P Rathnagiri1,3.
Abstract
This study was conducted to develop and evaluate protein-G-based lateral flow assay (LFA) for rapid serodiagnosis of brucellosis in various domesticated animal species. The assay diagnostic performance was tested with 144 reference and 356 field sera samples and then compared with other serological assays. Results revealed that LFA showed 89% and 99% sensitivity and specificity, respectively, when compared with competitive ELISA as the gold standard. This study demonstrated LFA alone as a potential serodiagnostic assay for rapid serodiagnosis of brucellosis in various domesticated animal species.Entities:
Keywords: Protein-G-based LFA; brucellosis; competitive enzyme-linked immunoassay (cELISA); point-of-care diagnosis
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Year: 2018 PMID： 30477402 DOI： 10.1080/15321819.2018.1541803
Source DB: PubMed Journal: J Immunoassay Immunochem ISSN： 1532-1819