Literature DB >> 304701

X chromosomes attached by their long arm: replication autonomy of the short arm adjacent to the inactive centromere.

P Maraschio, S Scappaticci, E Ferrari, M Fraccaro.   

Abstract

A 16 years old girl with Turner syndrome was found to have a 45,X/46,X,t(XqXq)?(q27q23) constitution. The two X chromosomes are attached by their long arms with loss of chromosome material and have one active and one inactive centromere. Analysis of replication patterns with autoradiography and BrdU treatment showed that the abnormal X is always the late replicating one and that the short arm of the second X which is adjacent to the inactive centromere maintains a degree of replication autonomy from the rest of the long arm.

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Year:  1977        PMID： 304701

Source DB:  PubMed          Journal:  Ann Genet        ISSN： 0003-3995


  7 in total

1.  The sequence of DNA replication in an iso-dicentric X-chromosome in peripheral blood lymphocytes and skin fibroblasts from the same individual.

Authors:  M S Lin; M G Wilson
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

2.  Genetic and cytological characterisation of fusion chromosomes of Dictyostelium discoideum.

Authors:  D L Welker; K L Williams
Journal:  Chromosoma       Date:  1981       Impact factor: 4.316

3.  Cd bands and centromeric function in dicentric chromosomes.

Authors:  P Maraschio; O Zuffardi; F Lo Curto
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

4.  Isodicentric X chromosome in a moderately tall patient with gonadal dysgenesis: lack of effect of functional centromere on inactivation pattern.

Authors:  J Robertson; M J Faed; M A Lamont; A M Crowder
Journal:  J Med Genet       Date:  1982-12       Impact factor: 6.318

5.  Further dicentric X isochromosomes and deletions, and a new structure i(X)(pter to q2102 to pter).

Authors:  A Daniel; T Saville; D B Southall
Journal:  J Med Genet       Date:  1979-08       Impact factor: 6.318

6.  Women heterozygous for deficiency of the (p21 leads to pter) region of the X chromosome are fertile.

Authors:  M Fraccaro; P Maraschio; F Pasquali; S Scappaticci
Journal:  Hum Genet       Date:  1977-12-23       Impact factor: 4.132

7.  Three related centromere proteins are absent from the inactive centromere of a stable isodicentric chromosome.

Authors:  W C Earnshaw; B R Migeon
Journal:  Chromosoma       Date:  1985       Impact factor: 4.316
  7 in total

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