Literature DB >> 3046890

Carbocysteine.

D T Brown1.   

Abstract

Carbocysteine is prescribed for conditions characterized by the accumulation of excessive mucus. Although often described as a mucolytic, its function is probably that of mucoregulation, which results in physical changes in accumulated secretions that are favorable in terms of clearance. The chemistry, pharmacology, pharmacokinetics, clinical applications, and toxicology of carbocysteine are reviewed.

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Year:  1988        PMID: 3046890     DOI: 10.1177/106002808802200721

Source DB:  PubMed          Journal:  Drug Intell Clin Pharm        ISSN: 0012-6578


  5 in total

1.  Use of slime dispersants to promote antibiotic penetration through the extracellular polysaccharide of mucoid Pseudomonas aeruginosa.

Authors:  C A Gordon; N A Hodges; C Marriott
Journal:  Antimicrob Agents Chemother       Date:  1991-06       Impact factor: 5.191

2.  Carbocisteine as a Modulator of Nrf2/HO-1 and NFκB Interplay in Rats: New Inspiration for the Revival of an Old Drug for Treating Ulcerative Colitis.

Authors:  Amir Mohamed Abdelhamid; Mahmoud E Youssef; Simona Cavalu; Gomaa Mostafa-Hedeab; Amal Youssef; Sara T Elazab; Samar Ibrahim; Shady Allam; Rehab Mohamed Elgharabawy; Eman El-Ahwany; Noha A Amin; Ahmed Shata; Osama A Mohammed; Mahmoud Said Ibrahim Abdeldaiem; Ahmed Alhowail; Gaber El-Saber Batiha; Engy A El-Mahmoudy; Maram Attia; Alaa Allam; Mona Y Zaater; Mona M Osman; Manar Nader; Aya Taha; Nada Abul Makarem; Sameh Saber
Journal:  Front Pharmacol       Date:  2022-06-08       Impact factor: 5.988

3.  Effect of carbocysteine on cough reflex to capsaicin in asthmatic patients.

Authors:  Yoshihisa Ishiura; Masaki Fujimura; Chihiro Yamamori; Kouichi Nobata; Shigeharu Myou; Kazuyoshi Kurashima; Yasukatsu Michishita; Tadayoshi Takegoshi
Journal:  Br J Clin Pharmacol       Date:  2003-06       Impact factor: 4.335

4.  Depolymerase improves gentamicin efficacy during Klebsiella pneumoniae induced murine infection.

Authors:  Shruti Bansal; Kusum Harjai; Sanjay Chhibber
Journal:  BMC Infect Dis       Date:  2014-08-23       Impact factor: 3.090

Review 5.  Clinical Efficacy of Carbocysteine in COPD: Beyond the Mucolytic Action.

Authors:  Elisabetta Pace; Isa Cerveri; Donato Lacedonia; Gregorino Paone; Alessandro Sanduzzi Zamparelli; Rossella Sorbo; Marcello Allegretti; Luigi Lanata; Francesco Scaglione
Journal:  Pharmaceutics       Date:  2022-06-14       Impact factor: 6.525

  5 in total

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