Literature DB >> 30467066

Molecular characterization of rotavirus diarrhea among children aged under five years in the Philippines, 2013-2015.

Joseph Bonifacio1, Socorro Lupisan2, Vito Roque3, Maria Joyce Ducusin3, Varja Grabovac4, Nyambat Batmunkh4, James D Heffelfinger4, Kimberley Fox4, Kohei Toda5, Maricel de Quiroz Castro5, Carl Kirkwood6, Amado Tandoc2.   

Abstract

With the availability of new and existing rotavirus vaccines, credible and reliable data on burden of rotavirus-associated disease are needed to enable evidence-based decision making regarding the introduction of rotavirus vaccines. The national rotavirus surveillance program in the Philippines, a sentinel-based surveillance, was established in 2012 to determine the proportion of laboratory-confirmed rotavirus cases among children under five years with acute gastroenteritis and to describe the geographic distribution and molecular epidemiology of rotavirus in the country. During 2013 to 2015, rotavirus infection was the cause of acute gastroenteritis among children under five years admitted to hospitals or evaluated in emergency rooms, constituting more than one-third of gastroenteritis hospitalizations at the sentinel site hospitals. The predominant genotype observed was G1P[8]. Although a rotavirus surveillance network has been established, findings suggest the need to strengthen the network in the country and to continue monitoring prevalent rotavirus strains to help identify the possible emergence of new strains.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Diarrhea; Gastroenteritis; Genotyping; Philippines; Rotavirus; Surveillance; Vaccine

Mesh:

Substances:

Year:  2018        PMID: 30467066     DOI: 10.1016/j.vaccine.2018.08.046

Source DB:  PubMed          Journal:  Vaccine        ISSN: 0264-410X            Impact factor:   3.641


  3 in total

Review 1.  Rotavirus infection in children in Southeast Asia 2008-2018: disease burden, genotype distribution, seasonality, and vaccination.

Authors:  Fajar Budi Lestari; Sompong Vongpunsawad; Nasamon Wanlapakorn; Yong Poovorawan
Journal:  J Biomed Sci       Date:  2020-05-21       Impact factor: 8.410

2.  Rotavirus gastroenteritis in Pakistan, 2018: updated disease burden.

Authors:  Nosheen Basharat; Asma Sadiq; Muhammad Dawood; Shahid Ali; Alam Khan; Rooh Ullah; Hayat Khan; Aamir Aziz; Hamid Ali; Aamer Ali Shah; Ijaz Ali; Jadoon Khan
Journal:  BMC Infect Dis       Date:  2021-05-06       Impact factor: 3.090

3.  Prevalence and genotypes distribution of group A rotavirus among outpatient children under 5 years with acute diarrhea in Shanghai, China, 2012-2018.

Authors:  Lijuan Lu; Huaqing Zhong; Ran Jia; Liyun Su; Menghua Xu; Lingfeng Cao; Pengcheng Liu; Yuanyun Ao; Niuniu Dong; Jin Xu
Journal:  BMC Gastroenterol       Date:  2022-05-03       Impact factor: 2.847

  3 in total

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