Literature DB >> 30466941

The toxicological analysis of lead and cadmium in prescription food for special medical purposes and modified milk products for newborns and infants available in Polish pharmacies.

Kamil Jurowski1, Mirosław Krośniak2, Maria Fołta2, Michael Cole3, Wojciech Piekoszewski4.   

Abstract

There is currently a lack of risk assessments around Pb and Cd in prescription food for special medical purposes (FSMPs) and modified milk products available in from pharmacies in Poland. This article describes and evaluates a toxicological analysis of lead and cadmium in prescription FSMPs (n = 6) and modified milk products (n = 6) available in Polish pharmacies. The metals were determined using electrothermal atomisation atomic absorption spectrometry. To make the appropriate risk assessment, we considered (1) the levels of lead and cadmium in a powdered product, (2) the amount of the metals consumed in one portion (single exposure), (3) the daily dose depending on age (months) and body weight and (4) the weekly intake of Pb and Cd in samples in comparison to provisional tolerable weekly intake (PTWI). The results demonstrated that the samples analysed do not represent a health hazard to newborns and infants. This study is important because of the concerns around the complex risk assessment of prescription FSMP's and modified milk products available in Polish pharmacies related to lead and cadmium.
Copyright © 2018 Elsevier GmbH. All rights reserved.

Entities:  

Keywords:  Atomic absorption spectrometry; Cadmium; Food for special medical purposes; Heavy metals; Infants; Lead; Newborns

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Year:  2018        PMID: 30466941     DOI: 10.1016/j.jtemb.2018.10.007

Source DB:  PubMed          Journal:  J Trace Elem Med Biol        ISSN: 0946-672X            Impact factor:   3.849


  4 in total

1.  The Toxicological Assessment of Content and Exposure of Heavy Metals (Pb and Cd) in Traditional Herbal Medicinal Products with Marshmallow Root (Althaea officinalis L., radix) from Polish Pharmacies.

Authors:  Kamil Jurowski; Mirosław Krośniak
Journal:  Toxics       Date:  2022-04-13

2.  The Level of Cadmium Impurities in Traditional Herbal Medicinal Products with Plantago lanceolata L., folium (Ribwort Plantain Leaves) Available in Polish Pharmacies - Comprehensive Toxicological Risk Assessment Including Regulatory Point of View and ICH Q3D Elemental Impurities Guideline.

Authors:  Kamil Jurowski; Maria Fołta; Barbara Tatar; Mirosław Krośniak
Journal:  Biol Trace Elem Res       Date:  2021-08-10       Impact factor: 4.081

3.  The Toxicological Risk Assessment of Lead and Cadmium in Valeriana officinalis L., radix (Valerian root) as Herbal Medicinal Product for the Relief of Mild Nervous Tension and Sleep Disorders Available in Polish Pharmacies.

Authors:  Kamil Jurowski; Maria Fołta; Barbara Tatar; Mehmet Berkoz; Mirosław Krośniak
Journal:  Biol Trace Elem Res       Date:  2021-04-01       Impact factor: 3.738

4.  The Toxicological Risk Assessment of Dermal Exposure of Patients Exposed to Nickel and Chromium due to Application of Ointments with Marjoram Herb Extract (Majoranae Herbae Extractum) Available in Polish Pharmacies.

Authors:  Kamil Jurowski; Maria Fołta; Barbara Tatar; Mehmet Berkoz; Mirosław Krośniak
Journal:  Biol Trace Elem Res       Date:  2021-06-30       Impact factor: 3.738

  4 in total

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