| Literature DB >> 30466767 |
Morna J Dorsey1, Jennifer M Puck2.
Abstract
In the United States, significant improvement in diagnosis and outcomes for children affected with severe combined immunodeficiency has followed institution of newborn screening using an assay to measure T-cell receptor excision circles in newborn dried blood spot specimens. Key to this outcome is the avoidance of infectious complications in infants with severe combined immunodeficiency.Entities:
Keywords: Hematopoietic cell transplant (HCT); Newborn screen (NBS); Severe combined immunodeficiency (SCID); T-cell lymphopenia; T-cell receptor excision circles (TRECs)
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Year: 2018 PMID： 30466767 DOI： 10.1016/j.iac.2018.08.002
Source DB: PubMed Journal: Immunol Allergy Clin North Am ISSN： 0889-8561 Impact factor: 3.479