| Literature DB >> 30466686 |
Abstract
Psoriasis is a chronic, immune-mediated, inflammatory skin disease that requires long-term therapy for disease control. This article reviews data presented in clinical trials to evaluate and compare various characteristics of biologics that are currently approved for the treatment of psoriasis. Attributes of biological agents that are examined in this article include efficacy, long-term maintenance, overall safety, median time to onset of efficacy, adjustment for body weight, frequency of injections, indication for psoriatic arthritis, and safety in pregnancy. Here, we evaluate what the ideal choice of biological therapy may be for psoriasis patients with specific needs.Entities:
Keywords: Biologics; Efficacy; Psoriasis; Psoriatic arthritis; Safety; Th17/IL-23 axis
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Year: 2018 PMID: 30466686 DOI: 10.1016/j.det.2018.07.004
Source DB: PubMed Journal: Dermatol Clin ISSN: 0733-8635 Impact factor: 3.478