| Literature DB >> 30464687 |
N A Nixon1, N Blais2, S Ernst3, C Kollmannsberger4, G Bebb1, M Butler5, M Smylie6, S Verma1.
Abstract
Immunotherapy has emerged as a new standard of care, showing survival benefit for solid tumours in multiple disease sites and indications. The survival improvements seen in diseases that were highly resistant to traditional therapies, with a poor prognosis, are unprecedented. Although the benefits observed in clinical trials are undeniable, not all patients derive those benefits, leading to emerging combination strategies and an ongoing quest for biomarker selection. Here, we summarize the current evidence for immunotherapy in the treatment of solid tumours, and we discuss emerging strategies at the forefront of research. We discuss future challenges that will be encountered as experience and knowledge continue to expand in this rapidly emerging field.Entities:
Keywords: Immuno-oncology
Mesh:
Substances:
Year: 2018 PMID: 30464687 PMCID: PMC6209564 DOI: 10.3747/co.25.3840
Source DB: PubMed Journal: Curr Oncol ISSN: 1198-0052 Impact factor: 3.677