Literature DB >> 30462504

Fragment-to-Lead Medicinal Chemistry Publications in 2017.

Paul N Mortenson1, Daniel A Erlanson2, Iwan J P de Esch3, Wolfgang Jahnke4, Christopher N Johnson1.   

Abstract

This Miniperspective is the third in a series reviewing fragment-to-lead publications from a given year. Following our reviews for 2015 and 2016, this Miniperspective provides tabulated summaries of relevant articles published in 2017 along with some general observations. In addition, we discuss insights obtained from analysis of the combined data set of 85 examples from all three years of publications.

Mesh：

Year:  2018        PMID： 30462504     DOI： 10.1021/acs.jmedchem.8b01472

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


  8 in total

1.  C(sp3)-H methylation enabled by peroxide photosensitization and Ni-mediated radical coupling.

Authors:  Aristidis Vasilopoulos; Shane W Krska; Shannon S Stahl
Journal:  Science       Date:  2021-04-23       Impact factor: 47.728

Review 2.  Unraveling Plant Natural Chemical Diversity for Drug Discovery Purposes.

Authors:  Emmanuelle Lautié; Olivier Russo; Pierre Ducrot; Jean A Boutin
Journal:  Front Pharmacol       Date:  2020-04-07       Impact factor: 5.810

Review 3.  Fragment-to-Lead Medicinal Chemistry Publications in 2020.

Authors:  Iwan J P de Esch; Daniel A Erlanson; Wolfgang Jahnke; Christopher N Johnson; Louise Walsh
Journal:  J Med Chem       Date:  2021-12-20       Impact factor: 7.446

4.  The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors-A Spin-Off Discovery from Fragment Screening.

Authors:  Sarah L Mueller; Panagiotis K Chrysanthopoulos; Maria A Halili; Caryn Hepburn; Tom Nebl; Claudiu T Supuran; Alessio Nocentini; Thomas S Peat; Sally-Ann Poulsen
Journal:  Molecules       Date:  2021-05-18       Impact factor: 4.411

5.  Discovery of new non-pyrimidine scaffolds as Plasmodium falciparum DHFR inhibitors by fragment-based screening.

Authors:  Marie Hoarau; Jarunee Vanichtanankul; Nitipol Srimongkolpithak; Danoo Vitsupakorn; Yongyuth Yuthavong; Sumalee Kamchonwongpaisan
Journal:  J Enzyme Inhib Med Chem       Date:  2021-12       Impact factor: 5.051

6.  Frag4Lead: growing crystallographic fragment hits by catalog using fragment-guided template docking.

Authors:  Alexander Metz; Jan Wollenhaupt; Steffen Glöckner; Niki Messini; Simon Huber; Tatjana Barthel; Ahmed Merabet; Hans Dieter Gerber; Andreas Heine; Gerhard Klebe; Manfred S Weiss
Journal:  Acta Crystallogr D Struct Biol       Date:  2021-08-23       Impact factor: 7.652

7.  Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions.

Authors:  Peter J Cossar; Madita Wolter; Lars van Dijck; Dario Valenti; Laura M Levy; Christian Ottmann; Luc Brunsveld
Journal:  J Am Chem Soc       Date:  2021-05-28       Impact factor: 15.419

Review 8.  Fragment-based drug discovery: opportunities for organic synthesis.

Authors:  Jeffrey D St Denis; Richard J Hall; Christopher W Murray; Tom D Heightman; David C Rees
Journal:  RSC Med Chem       Date:  2020-12-24
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.