Literature DB >> 30459513

Comparison of practical application steps of the previously used adrenaline auto injector in Turkey (EpiPen) and the currently available adrenaline auto injector (Penepin): a multi-center study.

Erdem Topal1, Hacer İlbilge Ertoy Karagöl2, Özlem Yılmaz3, Mustafa Arga4, Burcu Köksal5, Özlem Özbek Yılmaz5, Hülya Anıl6, Koray Harmancı6, Şeyhan Kutluğ7, Fadıl Öztürk7, Hasan Cem Razi8, İpek Türktaş9, Mehmet Sadık Demirsoy9, Arzu Bakırtaş9.   

Abstract

AIM: It has been shown by a great number of studies that the correct use of adrenaline auto injectors prescribed to patients with anaphylaxis is associated with the design of the auto injector, in addition to training. The aim of this study was to compare the skills of adults in using two different auto injectors prescribed to patients with anaphylaxis.
MATERIAL AND METHODS: Parents of patients aged between 1 and 18 years who referred to allergy outpatients were included in the study.
RESULTS: A total of 630 volunteers from nine centers were included in the study. Four hundred fifty-seven (72.5%) of the participants were females and 235 (37.3%) were undergraduates. The rate of showing all the steps of auto injector trainers correctly by the participants was found as (60.2%) (n=379) for EpiPen and 42.9% (n=270) for Penepin (p<0.001). The most frequent mistake with both auto injector trainers was the step of "place appropriate injection tip into outer thigh/press the trigger so it clicks." When the preferences of the volunteers were asked after training and application, 527 (83.7%) chose EpiPen, stating that it was easier and simpler to use.
CONCLUSIONS: Our study showed that the correct usage rates of both adrenaline auto injectors were much lower than expected and there could be mistakes in the application of both. It could be appropriate to make improvements in the design of Penepin, which is still the only available adrenaline auto injector in Turkey, such that its application steps will be simpler and quicker.

Entities:  

Keywords:  Adrenaline auto injector; EpiPen; Penepin; anaphylaxis

Year:  2018        PMID: 30459513      PMCID: PMC6239072          DOI: 10.5152/TurkPediatriArs.2018.6734

Source DB:  PubMed          Journal:  Turk Pediatri Ars


  9 in total

1.  Use assessment of self-administered epinephrine among food-allergic children and pediatricians.

Authors:  S H Sicherer; J A Forman; S A Noone
Journal:  Pediatrics       Date:  2000-02       Impact factor: 7.124

Review 2.  Anaphylaxis, killer allergy: long-term management in the community.

Authors:  F Estelle R Simons
Journal:  J Allergy Clin Immunol       Date:  2006-02       Impact factor: 10.793

3.  Auvi-Q versus EpiPen: preferences of adults, caregivers, and children.

Authors:  Carlos A Camargo; Adriana Guana; Sheldon Wang; F Estelle R Simons
Journal:  J Allergy Clin Immunol Pract       Date:  2013-04-09

4.  Parental use of EpiPen for children with food allergies.

Authors:  Jennifer S Kim; James M Sinacore; Jacqueline A Pongracic
Journal:  J Allergy Clin Immunol       Date:  2005-07       Impact factor: 10.793

5.  Make-up of the epinephrine autoinjector: the effect on its use by untrained users.

Authors:  Arzu Bakirtas; Mustafa Arga; Ferhat Catal; Oksan Derinoz; Mehmet S Demirsoy; Ipek Turktas
Journal:  Pediatr Allergy Immunol       Date:  2011-07-13       Impact factor: 6.377

6.  A real-life study on acquired skills from using an adrenaline autoinjector.

Authors:  Erdem Topal; Arzu Bakirtas; Ozlem Yilmaz; Ilbilge Hacer Ertoy; Mustafa Arga; Mehmet Sadik Demirsoy; Ipek Turktas
Journal:  Int Arch Allergy Immunol       Date:  2012-10-18       Impact factor: 2.749

7.  Effect of epinephrine autoinjector design on unintentional injection injury.

Authors:  Mustafa Arga; Arzu Bakirtas; Erdem Topal; Ozlem Yilmaz; Ilbilge Hacer Ertoy Karagol; M Sadik Demirsoy; Ipek Turktas
Journal:  Allergy Asthma Proc       Date:  2012 Nov-Dec       Impact factor: 2.587

8.  Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.

Authors:  Hugh A Sampson; Anne Muñoz-Furlong; Ronna L Campbell; N Franklin Adkinson; S Allan Bock; Amy Branum; Simon G A Brown; Carlos A Camargo; Rita Cydulka; Stephen J Galli; Jane Gidudu; Rebecca S Gruchalla; Allen D Harlor; David L Hepner; Lawrence M Lewis; Phillip L Lieberman; Dean D Metcalfe; Robert O'Connor; Antonella Muraro; Amanda Rudman; Cara Schmitt; Debra Scherrer; F Estelle R Simons; Stephen Thomas; Joseph P Wood; Wyatt W Decker
Journal:  J Allergy Clin Immunol       Date:  2006-02       Impact factor: 10.793

9.  Demonstration of epinephrine autoinjectors (EpiPen and Anapen) by pharmacists in a randomised, simulated patient assessment: acceptable, but room for improvement.

Authors:  Sandra M Salter; Richard Loh; Frank M Sanfilippo; Rhonda M Clifford
Journal:  Allergy Asthma Clin Immunol       Date:  2014-09-19       Impact factor: 3.406

  9 in total

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