| Literature DB >> 30457336 |
Kartikey Singh, Gaurav Sharma1, Manjulika Shukla, Ruchir Kant, Sidharth Chopra, Sanjeev K Shukla1, Rama P Tripathi1,2.
Abstract
An efficient synthesis of biaryl ethers, from electron-deficient aryl halides using NaH/DMSO under metal- and phenol-free conditions, has been achieved to access dibenzo-bistriazolo-1,4,7-oxadiazonines and vancomycin-like glyco-macrocycles. A 44-membered glyco-macrocycle showed promising activity against vancomycin-resistant Staphylococcus aureus (VRSA).Entities:
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Year: 2018 PMID： 30457336 DOI： 10.1021/acs.joc.8b01631
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354