Literature DB >> 30456646

Myths, reality and future of mesenchymal stem cell therapy.

R A Poltavtseva1, A V Poltavtsev2, G V Lutsenko2, E V Svirshchevskaya3.   

Abstract

Mesenchymal stem cell (MSC) therapy represents an alternative approach for tissue regeneration and inflammation control. In spite of a huge amount of preclinical data that has been accumulated on the therapeutic properties of MSCs, there are many conflicting results, possibly due to differences in the properties of MSCs obtained from different sources or underestimated mechanisms of MSC in vivo behavior. This review consolidates the in vivo effects of MSC therapy, discusses the fate of MSCs after intravascular and local delivery and proposes possible trends in MSC therapy.

Entities:  

Keywords:  Cell therapy; Diabetes mellitus; Exosomes; Liposomes; Mesenchymal stem cells

Mesh:

Substances:

Year:  2018        PMID: 30456646     DOI: 10.1007/s00441-018-2961-4

Source DB:  PubMed          Journal:  Cell Tissue Res        ISSN: 0302-766X            Impact factor:   5.249


  8 in total

Review 1.  Insights into the Secretome of Mesenchymal Stem Cells and Its Potential Applications.

Authors:  Sharon Eleuteri; Alessandra Fierabracci
Journal:  Int J Mol Sci       Date:  2019-09-17       Impact factor: 5.923

2.  Exosomes derived from M0, M1 and M2 macrophages exert distinct influences on the proliferation and differentiation of mesenchymal stem cells.

Authors:  Yu Xia; Xiao-Tao He; Xin-Yue Xu; Bei-Min Tian; Ying An; Fa-Ming Chen
Journal:  PeerJ       Date:  2020-04-24       Impact factor: 2.984

Review 3.  Exosome therapeutics for lung regenerative medicine.

Authors:  Kristen Popowski; Halle Lutz; Shiqi Hu; Arianna George; Phuong-Uyen Dinh; Ke Cheng
Journal:  J Extracell Vesicles       Date:  2020-06-29

Review 4.  Crosstalk between exosomes and autophagy: A review of molecular mechanisms and therapies.

Authors:  Huifang Xing; Jin Tan; Yuyang Miao; Yingmei Lv; Qiang Zhang
Journal:  J Cell Mol Med       Date:  2021-01-27       Impact factor: 5.310

Review 5.  Mesenchymal stromal cell-dependent immunoregulation in chemically-induced acute liver failure.

Authors:  Jia-Hang Zhou; Xuan Lu; Cui-Lin Yan; Xin-Yu Sheng; Hong-Cui Cao
Journal:  World J Stem Cells       Date:  2021-03-26       Impact factor: 5.326

6.  Resistance of Human Liver Mesenchymal Stem Cells to FAS-Induced Cell Death.

Authors:  Irina V Kholodenko; Alisa M Gisina; Garik V Manukyan; Alexander G Majouga; Elena V Svirshchevskaya; Roman V Kholodenko; Konstantin N Yarygin
Journal:  Curr Issues Mol Biol       Date:  2022-07-30       Impact factor: 2.976

Review 7.  Eph/ephrin Signaling and Biology of Mesenchymal Stromal/Stem Cells.

Authors:  David Alfaro; Mariano R Rodríguez-Sosa; Agustín G Zapata
Journal:  J Clin Med       Date:  2020-01-22       Impact factor: 4.241

8.  Establishment of a novel mesenchymal stem cell-based regimen for chronic myeloid leukemia differentiation therapy.

Authors:  Shiman Zuo; Luchen Sun; Yuxin Wang; Bing Chen; Jingyue Wang; Xiangyu Ge; Yan Lu; Nanfei Yang; Pingping Shen
Journal:  Cell Death Dis       Date:  2021-02-24       Impact factor: 8.469

  8 in total

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