Literature DB >> 30454835

Acute Alcoholic Hepatitis.

Gene Y Im1.   

Abstract

Alcoholic hepatitis is a unique type of alcohol-associated liver disease characterized by acute liver inflammation caused by prolonged heavy alcohol use. Treatment is mostly supportive. The short-term prognosis of acute alcoholic hepatitis depends on liver recovery, and ranges widely from rapid improvement to grim multiorgan failure despite treatment. Refinement of scoring systems have enhanced prognostication to guide clinical decision making in alcoholic hepatitis. Recent advances in the treatment of alcoholic hepatitis have solidified corticosteroids as the cornerstone of treatment to enhance short-term survival, but not intermediate or long-term survival.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Alcohol use disorder; Alcoholic hepatitis; Corticosteroids; Discriminant function; Hepatorenal syndrome; Lille score; N-acetylcysteine; Pentoxifylline

Mesh:

Substances:

Year:  2018        PMID: 30454835     DOI: 10.1016/j.cld.2018.09.005

Source DB:  PubMed          Journal:  Clin Liver Dis        ISSN: 1089-3261            Impact factor:   6.126


  8 in total

1.  Outcomes of Hospitalized Acute Alcoholic Hepatitis (AH) in Patients With Bipolar 1 Disorder (B1D).

Authors:  Alexander J Kaye; Shivani Patel; Sarah Meyers; Daniel Rim; Catherine Choi; Sushil Ahlawat
Journal:  Cureus       Date:  2022-05-27

2.  microRNA-155 Modulates Hepatic Stellate Cell Proliferation, Apoptosis, and Cell Cycle Progression in Rats With Alcoholic Hepatitis via the MAPK Signaling Pathway Through Targeting SOCS1.

Authors:  Dengtao Liu; Ping Han; Chunhai Gao; Wei Gao; Xiaocui Yao; Shulan Liu
Journal:  Front Pharmacol       Date:  2020-04-07       Impact factor: 5.810

3.  Chronic stress and corticosterone exacerbate alcohol-induced tissue injury in the gut-liver-brain axis.

Authors:  Pradeep K Shukla; Avtar S Meena; Kesha Dalal; Cherie Canelas; Geetha Samak; Joseph F Pierre; RadhaKrishna Rao
Journal:  Sci Rep       Date:  2021-01-12       Impact factor: 4.379

4.  Clinical Presentation and Gene Expression of Acute Alcohol-Induced Microvesicular Steatosis Mimicking Alcoholic Hepatitis.

Authors:  Laurent Spahr; Nicolas Lanthier; Mathieu Tihy; Jean-Louis Frossard; Laura Rubbia-Brandt; Nicolas Goossens
Journal:  Hepatol Commun       Date:  2021-01-09

5.  Central role of intestinal epithelial glucocorticoid receptor in alcohol- and corticosterone-induced gut permeability and systemic response.

Authors:  Pradeep K Shukla; Avtar S Meena; Joseph F Pierre; RadhaKrishna Rao
Journal:  FASEB J       Date:  2022-01       Impact factor: 5.834

6.  LncRNA 1700020I14Rik promotes AKR1B10 expression and activates Erk pathway to induce hepatocyte damage in alcoholic hepatitis.

Authors:  Yue Wu; Yabin Qi; Yangqiu Bai; Haihui Zhang; Wenliang Zhu; Shengli Zhou; Yanrui Zhang
Journal:  Cell Death Discov       Date:  2022-08-26

7.  Chronic Alcohol Exposure of Cells Using Controlled Alcohol-Releasing Capillaries.

Authors:  Wanil Kim; Hye-Seon Jeong; Sang-Chan Kim; Chang-Hyung Choi; Kyung-Ha Lee
Journal:  Cells       Date:  2021-05-06       Impact factor: 6.600

8.  Utility of platelet indices in alcoholic hepatitis: a retrospective study.

Authors:  Saravanakumari Vijayakumar; Stalin Viswanathan; Dheeraj Jain
Journal:  Porto Biomed J       Date:  2020-09-16
  8 in total

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