Literature DB >> 3045441

Double-blind, placebo-controlled lithium treatment in chemotherapy induced aplasia for AML: reduced antibiotic requirement.

S Collado1, D Charron, L Degos.   

Abstract

A double-blind placebo-controlled study on lithium (Li) therapy after chemotherapy-induced bone marrow aplasia was undertaken in 53 patients with acute myeloblastic leukemia (AML). No difference was observed between the two groups for the duration of aplasia, the number of units of platelets or RBC transfused, the complete remission rate or the disease free survival. However, a statistically significant reduction in the number of days of antibiotic therapy required was found in the treated group (10.55 +/- 2.72 vs 12.73 +/- 3.60, P less than 0.05).

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Year:  1988        PMID： 3045441     DOI： 10.1007/BF02985446

Source DB:  PubMed          Journal:  Med Oncol Tumor Pharmacother        ISSN： 0736-0118


  8 in total

1.  Lithium carbonate attenuation of chemotherapy-induced neutropenia.

Authors:  R S Stein; C Beaman; M Y Ali; R Hansen; D D Jenkins; H G Jume'an
Journal:  N Engl J Med       Date:  1977-08-25       Impact factor: 91.245

2.  Felty's syndrome. Effect of lithium on granulopoiesis.

Authors:  R C Gupta; W A Robinson; J E Kurnick
Journal:  Am J Med       Date:  1976-07       Impact factor: 4.965

3.  Lithium in acute myeloid leukaemia.

Authors:  D Charron; A J Barrett; A Faille; N Alby; T Schmitt; L Degos
Journal:  Lancet       Date:  1977-06-18       Impact factor: 79.321

4.  Effect of lithium on stem cell and stromal cell proliferation in vitro.

Authors:  M A Doukas; E Niskanen; P J Quesenberry
Journal:  Exp Hematol       Date:  1986-03       Impact factor: 3.084

5.  Neutrophil kinetics in Felty's syndrome.

Authors:  R A Joyce; D R Boggs; P A Chervenick; P Lalezari
Journal:  Am J Med       Date:  1980-11       Impact factor: 4.965

6.  Lithium and hematopoietic toxicity. I. Recovery in vivo of murine hematopoietic stem cells (CFU-S and CFU-Mix) after single-dose administration of cyclophosphamide.

Authors:  V S Gallicchio
Journal:  Exp Hematol       Date:  1986-06       Impact factor: 3.084

7.  Lithium carbonate in patients with small cell lung cancer receiving combination chemotherapy.

Authors:  G H Lyman; C C Williams; D Preston; A Goldman; W R Dinwoodie; H Saba; R Hartmann; R Jensen; L Shukovsky
Journal:  Am J Med       Date:  1981-06       Impact factor: 4.965

8.  The clinical laboratory and electroencephalographic effects of lithium.

Authors:  D Mayfield; R G Brown
Journal:  J Psychiatr Res       Date:  1966-12       Impact factor: 4.791
  8 in total
  1 in total

1.  The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.

Authors:  Versha Banerji; Stacey M Frumm; Kenneth N Ross; Loretta S Li; Anna C Schinzel; Cynthia K Hahn; Rose M Kakoza; Kwan T Chow; Linda Ross; Gabriela Alexe; Nicola Tolliday; Haig Inguilizian; Ilene Galinsky; Richard M Stone; Daniel J DeAngelo; Giovanni Roti; Jon C Aster; William C Hahn; Andrew L Kung; Kimberly Stegmaier
Journal:  J Clin Invest       Date:  2012-02-13       Impact factor: 14.808
  1 in total

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