Literature DB >> 30449377

Heart Failure with Reduced Ejection Fraction in Women: Epidemiology, Outcomes, and Treatment.

Gina Mentzer1, Eileen M Hsich2.   

Abstract

There are millions of people affected by heart failure with reduced ejection fraction (HFrEF) as diagnosed with ejection fraction 40% or less by imaging. Established therapies have been proven through clinical trials on lifestyle interventions, medications, and devices for HFrEF to improve quality of life, heart function, and survival. Although there are more men than women suffering with HFrEF, there are no prospectively proven, sex-specific guideline therapies because women have been underrepresented in clinical trials. Current recommendations for medications in women with HFrEF are described in this article.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cardiomyopathies; Sex differences; Systolic heart failure; Women

Mesh：

Year:  2018        PMID： 30449377      PMCID： PMC6298793          DOI： 10.1016/j.hfc.2018.08.003

Source DB:  PubMed          Journal:  Heart Fail Clin        ISSN： 1551-7136            Impact factor:   3.179


  41 in total

1.  A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure.

Authors:  J N Cohn; G Tognoni
Journal:  N Engl J Med       Date:  2001-12-06       Impact factor: 91.245

2.  Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial--the Losartan Heart Failure Survival Study ELITE II.

Authors:  B Pitt; P A Poole-Wilson; R Segal; F A Martinez; K Dickstein; A J Camm; M A Konstam; G Riegger; G H Klinger; J Neaton; D Sharma; B Thiyagarajan
Journal:  Lancet       Date:  2000-05-06       Impact factor: 79.321

3.  Sex differences in the prognosis of congestive heart failure: results from the Cardiac Insufficiency Bisoprolol Study (CIBIS II).

Authors:  T Simon; M Mary-Krause; C Funck-Brentano; P Jaillon
Journal:  Circulation       Date:  2001-01-23       Impact factor: 29.690

4.  Sex-based differences in the effect of digoxin for the treatment of heart failure.

Authors:  Saif S Rathore; Yongfei Wang; Harlan M Krumholz
Journal:  N Engl J Med       Date:  2002-10-31       Impact factor: 91.245

5.  Congestive heart failure in subjects with normal versus reduced left ventricular ejection fraction: prevalence and mortality in a population-based cohort.

Authors:  R S Vasan; M G Larson; E J Benjamin; J C Evans; C K Reiss; D Levy
Journal:  J Am Coll Cardiol       Date:  1999-06       Impact factor: 24.094

6.  Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction.

Authors:  Bertram Pitt; Willem Remme; Faiez Zannad; James Neaton; Felipe Martinez; Barbara Roniker; Richard Bittman; Steve Hurley; Jay Kleiman; Marjorie Gatlin
Journal:  N Engl J Med       Date:  2003-03-31       Impact factor: 91.245

7.  The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators.

Authors:  B Pitt; F Zannad; W J Remme; R Cody; A Castaigne; A Perez; J Palensky; J Wittes
Journal:  N Engl J Med       Date:  1999-09-02       Impact factor: 91.245

8.  Metoprolol CR/XL in female patients with heart failure: analysis of the experience in Metoprolol Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF).

Authors:  Jalal K Ghali; Ileana L Piña; Stephen S Gottlieb; Prakash C Deedwania; John C Wikstrand
Journal:  Circulation       Date:  2002-04-02       Impact factor: 29.690

9.  Efficacy of angiotensin-converting enzyme inhibitors and beta-blockers in the management of left ventricular systolic dysfunction according to race, gender, and diabetic status: a meta-analysis of major clinical trials.

Authors:  Paul G Shekelle; Michael W Rich; Sally C Morton; Col Sid W Atkinson; Wenli Tu; Margaret Maglione; Shannon Rhodes; Michael Barrett; Gregg C Fonarow; Barry Greenberg; Paul A Heidenreich; Tom Knabel; Marvin A Konstam; Anthony Steimle; Lynne Warner Stevenson
Journal:  J Am Coll Cardiol       Date:  2003-05-07       Impact factor: 24.094

10.  Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study.

Authors:  Milton Packer; Michael B Fowler; Ellen B Roecker; Andrew J S Coats; Hugo A Katus; Henry Krum; Paul Mohacsi; Jean L Rouleau; Michal Tendera; Christoph Staiger; Terry L Holcslaw; Ildiko Amann-Zalan; David L DeMets
Journal:  Circulation       Date:  2002-10-22       Impact factor: 29.690
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  17 in total

1.  Sex differences in outcomes following less-invasive left ventricular assist device implantation.

Authors:  Silvia Mariani; Tong Li; Karl Bounader; Dietmar Boethig; Alexandra Schöde; Jasmin S Hanke; Jana Michaelis; L Christian Napp; Dominik Berliner; Guenes Dogan; Roberto Lorusso; Axel Haverich; Jan D Schmitto
Journal:  Ann Cardiothorac Surg       Date:  2021-03

2.  Relationship between enteral nutrition and serum levels of inflammatory factors and cardiac function in elderly patients with heart failure: A protocol for systematic review and meta-analysis.

Authors:  Shutang Zhao; Xiren Wang
Journal:  Medicine (Baltimore)       Date:  2021-05-14       Impact factor: 1.889

3.  The heart failure specialists of tomorrow: a network for young cardiovascular scientists and clinicians.

Authors:  Markus S Anker; Claire Bouleti; Theodoros Christodoulides; Angela Durante; Edit Gara; Sara Hadzibegovic; Kalliopi Keramida; Alessia Lena; Angela Massouh; Ivan Milinkovic; Matthias P Nägele; Alexander Nossikoff; Rui Plácido; Tamás Radovits; Heli Tolppanen; Giuseppe Vergaro; Markus Wallner; Sophie Welch; Yuri Lopatin; Mitja Lainscak; Alexandre Mebazaa; Andrew J S Coats; Petar M Seferović; Ewa A Jankowska
Journal:  ESC Heart Fail       Date:  2020-04-30

4.  Impact of sex, socio-economic status, and remoteness on therapy and survival in heart failure.

Authors:  Sarah J Gutman; Ben T Costello; Stavroula Papapostolou; Leah Iles; Johnson Ja; James L Hare; Andris Ellims; Thomas H Marwick; Andrew J Taylor
Journal:  ESC Heart Fail       Date:  2019-10-16

5.  The prevalence of left ventricular thrombus among patients with low ejection fraction by trans-thoracic echocardiography.

Authors:  Nouradden Noman Aljaber; Zohoor Ali Mattash; Sultan Abdulwadoud Alshoabi; Fahad Hassan Alhazmi
Journal:  Pak J Med Sci       Date:  2020 May-Jun       Impact factor: 1.088

Review 6.  Surrogate cardiovascular outcomes with sodium-glucose co-transporter-2 inhibitors in women: An updated meta-analysis.

Authors:  Dimitrios Patoulias; Christodoulos Papadopoulos; Michael Doumas
Journal:  Indian Heart J       Date:  2020-12-25

Review 7.  Real-World Safety of Sacubitril/Valsartan in Women and Men With Heart Failure and Reduced Ejection Fraction: A Meta-analysis.

Authors:  Kaitlin Nuechterlein; Ahmed AlTurki; Jiayi Ni; Manuel Martínez-Sellés; Pieter Martens; Vincenzo Russo; Charlotte Nordberg Backelin; Thao Huynh
Journal:  CJC Open       Date:  2021-09-15

8.  Comparable outcomes between genders in patients undergoing surgical ventricular reconstruction for ischaemic heart failure.

Authors:  Serenella Castelvecchio; Valentina Milani; Marianna Volpe; Michele Citarella; Federico Ambrogi; Sara Boveri; Guglielmo Saitto; Andrea Garatti; Lorenzo Menicanti
Journal:  ESC Heart Fail       Date:  2020-11-10

9.  Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction: GALACTIC-HF baseline characteristics and comparison with contemporary clinical trials.

Authors:  John R Teerlink; Rafael Diaz; G Michael Felker; John J V McMurray; Marco Metra; Scott D Solomon; Kirkwood F Adams; Inder Anand; Alexandra Arias-Mendoza; Tor Biering-Sørensen; Michael Böhm; Diana Bonderman; John G F Cleland; Ramon Corbalan; Maria G Crespo-Leiro; Ulf Dahlström; Luis E Echeverria Correa; James C Fang; Gerasimos Filippatos; Cândida Fonseca; Eva Goncalvesova; Assen R Goudev; Jonathan G Howlett; David E Lanfear; Mayanna Lund; Peter Macdonald; Vyacheslav Mareev; Shin-Ichi Momomura; Eileen O'Meara; Alexander Parkhomenko; Piotr Ponikowski; Felix J A Ramires; Pranas Serpytis; Karen Sliwa; Jindrich Spinar; Thomas M Suter; Janos Tomcsanyi; Hans Vandekerckhove; Dragos Vinereanu; Adriaan A Voors; Mehmet B Yilmaz; Faiez Zannad; Lucie Sharpsten; Jason C Legg; Siddique A Abbasi; Claire Varin; Fady I Malik; Christopher E Kurtz
Journal:  Eur J Heart Fail       Date:  2020-10-27       Impact factor: 15.534

10.  National trends in heart failure mortality in men and women, United Kingdom, 2000-2017.

Authors:  Clare J Taylor; José M Ordóñez-Mena; Nicholas R Jones; Andrea K Roalfe; Sarah Lay-Flurrie; Tom Marshall; F D Richard Hobbs
Journal:  Eur J Heart Fail       Date:  2020-09-23       Impact factor: 17.349
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