| Literature DB >> 30446893 |
Stefan Unterecker1, Gudrun Hefner2, Pierre Baumann3, Gerd Gründer4, Niels Bergemann5, Hans-Willi Clement6, Andreas Conca7, Jürgen Deckert8, Katharina Domschke9,10, Gabriel Eckermann11, Karin Egberts12, Manfred Gerlach12, Christine Greiner13, Ekkehard Haen14, Ursula Havemann-Reinecke15, Renate Helmer16, Ger Janssen17, Eveline Jaquenoud18, Gerd Laux19, Thomas Messer20, Rainald Mössner21, Matthias J Müller22, Michael Paulzen23,24, Bruno Pfuhlmann25, Peter Riederer8, Alois Saria26, Bernd Schoppek27, Georgios Schoretsanitis28, Markus Schwarz29, Margarethe Silva Gracia14, Benedikt Stegmann14, Werner Steimer30, Julia C Stingl13, Manfred Uhr31, Sven Ulrich32, Roland Waschgler33, Gerald Zernig26,34, Gabriele Zurek35, Christoph Hiemke36,37.
Abstract
Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug concentrations in blood serum or plasma to optimize pharmacological therapy. TDM is an instrument with which the high interindividual variability of pharmacokinetics of patients can be identified and therefore enables a personalized pharmacotherapy. In September 2017 the TDM task force of the Working Group for Neuropsychopharmacology and Pharmacopsychiatry (AGNP) published an update of the consensus guidelines on TDM published in 2011. This article summarizes the essential statements for the clinical practice in psychiatry and neurology.Entities:
Keywords: Dose-related reference range; Drug concentration; Neuropsychotropic drugs; Psychopharmacotherapy; Therapeutic reference range
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Year: 2019 PMID： 30446893 DOI： 10.1007/s00115-018-0643-9
Source DB: PubMed Journal: Nervenarzt ISSN： 0028-2804 Impact factor: 1.214