Literature DB >> 30445839

Flavonoids: biological activities and therapeutic potential.

Mércia Marques Jucá1, Francisco Mauricio Sales Cysne Filho1, Jamily Cunha de Almeida2, Dara da Silva Mesquita3, Jéssica Rodrigues de Moraes Barriga3, Kátia Cilene Ferreira Dias1, Talita Matias Barbosa1, Luna Costa Vasconcelos1, Luzia Kalyne Almeida Moreira Leal1, José Eduardo Ribeiro3, Silvânia Maria Mendes Vasconcelos1.   

Abstract

Flavonoids have aroused much interest in research, since they present a great diversity of biological activities observed in vitro, such as: antioxidant effect, modulation of the enzymatic activity and inhibition of cellular proliferation, exerting beneficial effects on the organism, as well as the use of its therapeutic potential. With wide distribution in the plant kingdom represent a class of phenolic compounds that differ in their chemical structure and particular characteristics. The objective of this review was to describe the relevant aspects of flavonoids, reporting the different known groups, the probable mechanisms by which they act, their pharmacological properties and to gain a better understanding of the reported beneficial health effects of these substances. This systematic review consisted of research using scientific databases such as Scopus, Science Direct, PubMed, SciVerse and SciELO, without time limitation. Some pharmacological properties of some flavonoids and their health benefits have been confirmed by previous studies.

Entities:  

Keywords:  Flavonoids; antioxidant effect; biological activity; therapeutic potential

Mesh:

Substances:

Year:  2018        PMID: 30445839     DOI: 10.1080/14786419.2018.1493588

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  34 in total

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2.  Snailase: A Promising Tool for the Enzymatic Hydrolysis of Flavonoid Glycosides From Plant Extracts.

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Review 4.  Delving the Role of Caralluma fimbriata: An Edible Wild Plant to Mitigate the Biomarkers of Metabolic Syndrome.

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Review 5.  New perspectives on natural flavonoids on COVID-19-induced lung injuries.

Authors:  Fernanda Paula R Santana; Fernanda Thevenard; Kaio S Gomes; Laura Taguchi; Niels Olsen S Câmara; Roberta S Stilhano; Rodrigo P Ureshino; Carla Maximo Prado; João Henrique Ghilardi Lago
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6.  The Callus of Phaseolus coccineus and Glycine max Biotransform Flavanones into the Corresponding Flavones.

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7.  Kaempferol Facilitated Extinction Learning in Contextual Fear Conditioned Rats via Inhibition of Fatty-Acid Amide Hydrolase.

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8.  Evaluation of flavonoids as 2019-nCoV cell entry inhibitor through molecular docking and pharmacological analysis.

Authors:  Deep Bhowmik; Rajat Nandi; Amresh Prakash; Diwakar Kumar
Journal:  Heliyon       Date:  2021-03-14

9.  Antidiabetic and Hypolipidemic Effects of 5,7-Dimethoxyflavone in Streptozotocin-Induced Diabetic Rats.

Authors:  Yongli Xie; Yawei Zhang; Xiaoqing Su
Journal:  Med Sci Monit       Date:  2019-12-23

Review 10.  Protective Role of St. John's Wort and Its Components Hyperforin and Hypericin against Diabetes through Inhibition of Inflammatory Signaling: Evidence from In Vitro and In Vivo Studies.

Authors:  Michela Novelli; Pellegrino Masiello; Pascale Beffy; Marta Menegazzi
Journal:  Int J Mol Sci       Date:  2020-10-30       Impact factor: 5.923

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