Matin Khosravi-Largani1, Marzieh Nojomi2, Rokhsareh Aghili3, Hamidreza Alizadeh Otaghvar4, Kiarash Tanha5, Seyyed Hashem Sezavar Seyedi6, Azadeh Mottaghi7. 1. Medical Student, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. 2. Department of Community and Family Medicine, Preventive Medicine & Public Health Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. 3. Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran. 4. Trauma and Injury Research Center, Iran University of Medical Sciences, Tehran, Iran. 5. Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran. 6. Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology & Metabolism, Iran University of Medical Sciences, Tehran, Iran. 7. Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology & Metabolism, Iran University of Medical Sciences, Tehran, Iran. mottaghi.a@iums.ac.ir.
Abstract
BACKGROUND: Considering conflicting results on the consequences of all types of obesity surgery, we were to summarize them via a systematic review. METHODS: Electronic literature search was done via scientific search engines. After the removal of duplicates and selection of articles of interest, 771 studies were included. RESULTS: Insulin resistance indicators were significantly improved after bariatric surgery. Leptin was also significantly decreased while adiponectin was significantly increased. Although the level of metabolic hormones changed after bariatric surgery, they were not statistically significant. Inflammation indicators were significantly decreased. Significant reduction was also detected in PAI-1 and sICAM-1. CONCLUSIONS: Bariatric surgery is beneficial in morbidly obese patients. Although treating obesity in a surgical way may cause some complications, the weight loss is generally safe and effective.
BACKGROUND: Considering conflicting results on the consequences of all types of obesity surgery, we were to summarize them via a systematic review. METHODS: Electronic literature search was done via scientific search engines. After the removal of duplicates and selection of articles of interest, 771 studies were included. RESULTS:Insulin resistance indicators were significantly improved after bariatric surgery. Leptin was also significantly decreased while adiponectin was significantly increased. Although the level of metabolic hormones changed after bariatric surgery, they were not statistically significant. Inflammation indicators were significantly decreased. Significant reduction was also detected in PAI-1 and sICAM-1. CONCLUSIONS: Bariatric surgery is beneficial in morbidly obesepatients. Although treating obesity in a surgical way may cause some complications, the weight loss is generally safe and effective.
Authors: David E Cummings; Joost Overduin; Michael H Shannon; Karen E Foster-Schubert Journal: Surg Obes Relat Dis Date: 2005 May-Jun Impact factor: 4.734
Authors: Abishek Iyer; David P Fairlie; Johannes B Prins; Bruce D Hammock; Lindsay Brown Journal: Nat Rev Endocrinol Date: 2010-02 Impact factor: 43.330
Authors: Luis Alberto Vázquez; Fernando Pazos; José Ramón Berrazueta; Carlos Fernández-Escalante; María Teresa García-Unzueta; Julio Freijanes; José Antonio Amado Journal: J Clin Endocrinol Metab Date: 2004-10-26 Impact factor: 5.958
Authors: Ralph Peterli; Robert E Steinert; Bettina Woelnerhanssen; Thomas Peters; Caroline Christoffel-Courtin; Markus Gass; Beatrice Kern; Markus von Fluee; Christoph Beglinger Journal: Obes Surg Date: 2012-05 Impact factor: 4.129
Authors: Kajsa Sjöholm; Lena M S Carlsson; Per-Arne Svensson; Johanna C Andersson-Assarsson; Felipe Kristensson; Peter Jacobson; Markku Peltonen; Magdalena Taube Journal: Diabetes Care Date: 2022-02-01 Impact factor: 19.112
Authors: Stanisław Głuszek; Arkadiusz Bociek; Edyta Suliga; Jarosław Matykiewicz; Magdalena Kołomańska; Piotr Bryk; Przemysław Znamirowski; Łukasz Nawacki; Martyna Głuszek-Osuch; Iwona Wawrzycka; Dorota Kozieł Journal: Int J Environ Res Public Health Date: 2020-07-24 Impact factor: 3.390
Authors: Khairul Anwar Zarkasi; Nor Azian Abdul Murad; Norfazilah Ahmad; Rahman Jamal; Noraidatulakma Abdullah Journal: Int J Environ Res Public Health Date: 2022-01-06 Impact factor: 3.390