Yukako Tsujimoto1, Mai Morimoto1, Naotaka Nitta2, Iwaki Akiyama3. 1. Medical Ultrasound Research Center, Doshisha University, 1-3 Tataramiyakodani, Kyotanabe, Kyoto, Japan. 2. National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan. 3. Medical Ultrasound Research Center, Doshisha University, 1-3 Tataramiyakodani, Kyotanabe, Kyoto, Japan. iakiyama@mail.doshisha.ac.jp.
Abstract
PURPOSE: Tissue characterization in terms of the differences in thermo-physical properties of biological tissues was investigated in this study. The objective was to measure the ratio of variation in sound velocity due to ultrasonic heating and to derive the relational expression between the ratio and thermo-physical properties. METHODS: The ratio of sound velocity variation before and after the temperature rise of tissue samples exposed to ultrasound was measured by ultrasonic pulse echo method. The thermo-physical properties were estimated for a tissue-mimicking material and porcine muscle and fat tissues due to theoretical expression. The transducer for heating had a resonance frequency of 3.2 MHz, and the transducer for measurement of sound velocity variation had a resonance frequency of 5.2 MHz. RESULTS: In the phantom study, the measured values of the temperature rise agreed with the values calculated by a finite element method (FEM). The estimated values of the temperature rise from the sound velocity variations of muscle and fat tissues were 0.36 °C and 1.1 °C, respectively. Also, the estimated values of thermo-physical properties agreed with the reference values within an error of 10%. CONCLUSIONS: The thermo-physical properties of the porcine tissues were measured by sound velocity variation due to ultrasonic heating within the safety regulations.
PURPOSE: Tissue characterization in terms of the differences in thermo-physical properties of biological tissues was investigated in this study. The objective was to measure the ratio of variation in sound velocity due to ultrasonic heating and to derive the relational expression between the ratio and thermo-physical properties. METHODS: The ratio of sound velocity variation before and after the temperature rise of tissue samples exposed to ultrasound was measured by ultrasonic pulse echo method. The thermo-physical properties were estimated for a tissue-mimicking material and porcine muscle and fat tissues due to theoretical expression. The transducer for heating had a resonance frequency of 3.2 MHz, and the transducer for measurement of sound velocity variation had a resonance frequency of 5.2 MHz. RESULTS: In the phantom study, the measured values of the temperature rise agreed with the values calculated by a finite element method (FEM). The estimated values of the temperature rise from the sound velocity variations of muscle and fat tissues were 0.36 °C and 1.1 °C, respectively. Also, the estimated values of thermo-physical properties agreed with the reference values within an error of 10%. CONCLUSIONS: The thermo-physical properties of the porcine tissues were measured by sound velocity variation due to ultrasonic heating within the safety regulations.
Keywords:
Sound velocity variation; Temperature rise; Thermo-physical properties; Tissue characterization
Authors: Sitaramanjaneya Reddy Guntur; Kang Il Lee; Dong-Guk Paeng; Andrew John Coleman; Min Joo Choi Journal: Ultrasound Med Biol Date: 2013-08-09 Impact factor: 2.998
Authors: Carmen Fierbinteanu Braticevici; Ioan Sporea; Eugenia Panaitescu; Laura Tribus Journal: Ultrasound Med Biol Date: 2013-08-09 Impact factor: 2.998