Amanda M Eudy1,2, Gary McDaniel3,4, William W Hurd3,4, Megan E B Clowse3,4. 1. From the Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA. amanda.eudy@duke.edu. 2. A.M. Eudy, PhD, Postdoctoral Associate, Division of Rheumatology and Immunology, Duke University Medical Center; G. McDaniel, PA-C, Clinical Research Coordinator, Division of Rheumatology and Immunology, Duke University Medical Center; W.W. Hurd, MD, MSc, MPH, Professor and Director, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Duke University Medical Center; M.E. Clowse, MD, MPH, Associate Professor of Medicine, Division of Rheumatology and Immunology, Duke University Medical Center. amanda.eudy@duke.edu. 3. From the Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA. 4. A.M. Eudy, PhD, Postdoctoral Associate, Division of Rheumatology and Immunology, Duke University Medical Center; G. McDaniel, PA-C, Clinical Research Coordinator, Division of Rheumatology and Immunology, Duke University Medical Center; W.W. Hurd, MD, MSc, MPH, Professor and Director, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Duke University Medical Center; M.E. Clowse, MD, MPH, Associate Professor of Medicine, Division of Rheumatology and Immunology, Duke University Medical Center.
Abstract
OBJECTIVE: We sought to identify causes for infertility in women with and without rheumatoid arthritis (RA). METHODS: Women with RA were matched to healthy controls. Differences in anti-Müllerian hormone (AMH) and anovulation were analyzed. RESULTS: Women with RA had lower AMH (β -1.05, 95% CI -2.09 to -0.005), but no difference was observed when AMH was log-transformed. No difference in anovulation was observed. Infertility prevalence was similar between groups, primarily attributable to polycystic ovary syndrome in healthy controls but largely unexplained in women with RA. CONCLUSION: AMH was lower in women with RA, but reasons for infertility among women with RA remain unknown.
OBJECTIVE: We sought to identify causes for infertility in women with and without rheumatoid arthritis (RA). METHODS:Women with RA were matched to healthy controls. Differences in anti-Müllerian hormone (AMH) and anovulation were analyzed. RESULTS:Women with RA had lower AMH (β -1.05, 95% CI -2.09 to -0.005), but no difference was observed when AMH was log-transformed. No difference in anovulation was observed. Infertility prevalence was similar between groups, primarily attributable to polycystic ovary syndrome in healthy controls but largely unexplained in women with RA. CONCLUSION:AMH was lower in women with RA, but reasons for infertility among women with RA remain unknown.
Authors: Vinita M Alexander; Jillian Ashley-Martin; Joan K Riley; Amber R Cooper; Valerie S Ratts; Emily S Jungheim Journal: Reprod Biomed Online Date: 2021-03-31 Impact factor: 4.567
Authors: Sara Patricia Peña-Lizola; Luis Humberto Sordia-Hernandez; Selene Marysol Garcia-Luna; Otto Valdes-Martinez; Cassandra Michele Skinner-Taylor; Mario Alberto Garza-Elizondo; Oscar Vidal-Gutierrez; Jesus Zacarias Villarreal-Perez; Miryam Eguia-Bernal; Felipe Arturo Morales-Martinez Journal: J Family Reprod Health Date: 2021-12