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Literature DB >> 30442291

The Clinical Course of a Genetic Dilated Cardiomyopathy: Letting the Cat Out of the BAG3.

Robin M Shaw¹, Andriana P Nikolova².

Abstract

Entities: Chemical Disease Gene Species

Keywords: BAG3; genetic cardiomyopathy; heart failure; personalized medicine

Mesh：

Substances：

Year: 2018 PMID： 30442291 PMCID： PMC6478168 DOI： 10.1016/j.jacc.2018.08.2180

Source DB: PubMed Journal: J Am Coll Cardiol ISSN： 0735-1097 Impact factor: 24.094

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12 in total

1. Dilated Cardiomyopathy Due to BLC2-Associated Athanogene 3 (BAG3) Mutations.

Authors: Fernando Domínguez; Sofía Cuenca; Zofia Bilińska; Rocío Toro; Eric Villard; Roberto Barriales-Villa; Juan Pablo Ochoa; Folkert Asselbergs; Arjan Sammani; Maria Franaszczyk; Mohammed Akhtar; Maria José Coronado-Albi; Diego Rangel-Sousa; Jose F Rodriguez-Palomares; Juan Jiménez-Jáimez; José Manuel Garcia-Pinilla; Tomás Ripoll-Vera; Maria Victoria Mogollón-Jiménez; Ana Fontalba-Romero; Dolores Garcia-Medina; Julian Palomino-Doza; David de Gonzalo-Calvo; Marcos Cicerchia; Joel Salazar-Mendiguchia; Clara Salas; Sabine Pankuweit; Thomas Morris Hey; Jens Mogensen; Paul J Barton; Philippe Charron; Perry Elliott; Pablo Garcia-Pavia
Journal: J Am Coll Cardiol Date: 2018-11-13 Impact factor: 24.094

2. GJA1-20k Arranges Actin to Guide Cx43 Delivery to Cardiac Intercalated Discs.

Authors: Wassim A Basheer; Shaohua Xiao; Irina Epifantseva; Ying Fu; Andre G Kleber; TingTing Hong; Robin M Shaw
Journal: Circ Res Date: 2017-09-18 Impact factor: 17.367

Review 3. Dilated cardiomyopathy: the complexity of a diverse genetic architecture.

Authors: Ray E Hershberger; Dale J Hedges; Ana Morales
Journal: Nat Rev Cardiol Date: 2013-07-30 Impact factor: 32.419

4. BAG3 and Hsc70 interact with actin capping protein CapZ to maintain myofibrillar integrity under mechanical stress.

Authors: Akinori Hishiya; Toshio Kitazawa; Shinichi Takayama
Journal: Circ Res Date: 2010-09-30 Impact factor: 17.367

5. Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes.

Authors: Takuro Arimura; Taisuke Ishikawa; Shinichi Nunoda; Sachio Kawai; Akinori Kimura
Journal: Hum Mutat Date: 2011-09-29 Impact factor: 4.878

6. A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.

Authors: Luke M Judge; Juan A Perez-Bermejo; Annie Truong; Alexandre Js Ribeiro; Jennie C Yoo; Christina L Jensen; Mohammad A Mandegar; Nathaniel Huebsch; Robyn M Kaake; Po-Lin So; Deepak Srivastava; Beth L Pruitt; Nevan J Krogan; Bruce R Conklin
Journal: JCI Insight Date: 2017-07-20

7. BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes.

Authors: Arthur M Feldman; Jennifer Gordon; JuFang Wang; Jianliang Song; Xue-Qian Zhang; Valerie D Myers; Douglas G Tilley; Erhe Gao; Nicholas E Hoffman; Dhanendra Tomar; Muniswamy Madesh; Joseph Rabinowitz; Walter J Koch; Feifei Su; Kamel Khalili; Joseph Y Cheung
Journal: J Mol Cell Cardiol Date: 2016-01-19 Impact factor: 5.000

The Clinical Course of a Genetic Dilated Cardiomyopathy: Letting the Cat Out of the BAG3.

1. Dilated Cardiomyopathy Due to BLC2-Associated Athanogene 3 (BAG3) Mutations.

2. GJA1-20k Arranges Actin to Guide Cx43 Delivery to Cardiac Intercalated Discs.

Review 3. Dilated cardiomyopathy: the complexity of a diverse genetic architecture.

4. BAG3 and Hsc70 interact with actin capping protein CapZ to maintain myofibrillar integrity under mechanical stress.

5. Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes.

6. A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.

7. BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes.

8. Familial Dilated Cardiomyopathy Caused by a Novel Frameshift in the BAG3 Gene.

9. Cx43 Isoform GJA1-20k Promotes Microtubule Dependent Mitochondrial Transport.

10. The Multifunctional Protein BAG3: A Novel Therapeutic Target in Cardiovascular Disease.

1. Genotype-Phenotype Correlation in Familial BAG3 Mutation Dilated Cardiomyopathy.