A Wireless Platform to Support Pre-Clinical Trial of Neural Implant for Spinal Cord Injury.

The efficacy of many clinical applications of electrical stimulation is currently gauged only by patients' verbal feedback or through the use of an independent system, limiting physicians' ability to provide quality treatment. By integrating neural response recording into the system, though, more accurate measures of treatment effectiveness are possible. This paper presents a platform which enables wireless control of an implantable bioelectronic device which integrates functional electrical stimulation and simultaneous recording of neural activity for a wide range of potential applications including motor function prostheses for spinal cord injury, retinal prostheses, and treatments for various other conditions. The proposed wireless platform utilizes a mobile application to offer a user-friendly integrated interface that enables setup and execution of stimulation and collection of recording data in animal studies. This platform will also support the continuing development of closed-loop neuromodulation strategies for investigating potential therapies for various diseases.